Psychiatric Diagnoses and Treatment Preceding Schizophrenia in Adolescents Aged 9–17 Years

ObjectiveOur study aimed to examine psychiatric diagnoses and treatment preceding a schizophrenia diagnosis in adolescents, stratified by sex and race/ethnicity.MethodsUsing Medicaid physical and behavioral health and pharmacy claims data, we identified 1,459 adolescents who were aged 9–17 years and...

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Main Authors: Christina D. Kang-Yi, Brian Chao, Shelly Teng, Jill Locke, David S. Mandell, Yin-Ling Irene Wong, C. Neill Epperson
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2020.00487/full
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author Christina D. Kang-Yi
Christina D. Kang-Yi
Brian Chao
Shelly Teng
Jill Locke
David S. Mandell
David S. Mandell
Yin-Ling Irene Wong
C. Neill Epperson
author_facet Christina D. Kang-Yi
Christina D. Kang-Yi
Brian Chao
Shelly Teng
Jill Locke
David S. Mandell
David S. Mandell
Yin-Ling Irene Wong
C. Neill Epperson
author_sort Christina D. Kang-Yi
collection DOAJ
description ObjectiveOur study aimed to examine psychiatric diagnoses and treatment preceding a schizophrenia diagnosis in adolescents, stratified by sex and race/ethnicity.MethodsUsing Medicaid physical and behavioral health and pharmacy claims data, we identified 1,459 adolescents who were aged 9–17 years and diagnosed with schizophrenia between January 2006 through June 2009. Psychiatric diagnosis, mental health service use including psychiatric hospitalization, residential treatment and outpatient therapy and psychotropic medication use preceding schizophrenia were identified.ResultsForty-five percent of the adolescents were diagnosed with one or more psychiatric conditions. More than 40% of the adolescents were hospitalized or placed in a residential treatment facility for other psychiatric conditions preceding schizophrenia. Overall, 72% of the adolescents were prescribed with one or more psychotropic medications and 22% were prescribed with three or more psychotropic medications in the year prior to their first schizophrenia diagnosis. We found that sex and race/ethnicity influence preceding psychiatric conditions and psychiatric treatment use.ConclusionsCareful screening and evaluation to validate diagnoses is important as the presence of certain psychiatric morbidity is common among adolescents with schizophrenia during the prodromal period. Developing acceptable and accessible interventions that will reduce psychiatric hospitalization and residential treatment care and improve care connection for schizophrenia treatment is important to mitigate complexity in treatment for adolescents and reduce cost burden for families and the society. Integrating health claims data in the development of schizophrenia risk conversion models can be useful in effectively predicting ideal timing of tailored interventions for adolescents with preceding psychiatric conditions.
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spelling doaj.art-a3d8bf4769284398966e17b3260702112022-12-22T01:28:44ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402020-06-011110.3389/fpsyt.2020.00487532869Psychiatric Diagnoses and Treatment Preceding Schizophrenia in Adolescents Aged 9–17 YearsChristina D. Kang-Yi0Christina D. Kang-Yi1Brian Chao2Shelly Teng3Jill Locke4David S. Mandell5David S. Mandell6Yin-Ling Irene Wong7C. Neill Epperson8Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United StatesThe Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, United StatesDepartment of Education, Loyola Marymount University, Los Angeles, CA, United StatesIcahn School of Medicine at Mount Sinai, New York, NY, United StatesSpeech and Hearing Sciences, University of Washington, Seattle, WA, United StatesDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United StatesThe Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, United StatesSchool of Social Policy and Practice, University of Pennsylvania, Philadelphia, PA, United StatesDepartment of Psychiatry, School of Medicine, University of Colorado, Denver, CO, United StatesObjectiveOur study aimed to examine psychiatric diagnoses and treatment preceding a schizophrenia diagnosis in adolescents, stratified by sex and race/ethnicity.MethodsUsing Medicaid physical and behavioral health and pharmacy claims data, we identified 1,459 adolescents who were aged 9–17 years and diagnosed with schizophrenia between January 2006 through June 2009. Psychiatric diagnosis, mental health service use including psychiatric hospitalization, residential treatment and outpatient therapy and psychotropic medication use preceding schizophrenia were identified.ResultsForty-five percent of the adolescents were diagnosed with one or more psychiatric conditions. More than 40% of the adolescents were hospitalized or placed in a residential treatment facility for other psychiatric conditions preceding schizophrenia. Overall, 72% of the adolescents were prescribed with one or more psychotropic medications and 22% were prescribed with three or more psychotropic medications in the year prior to their first schizophrenia diagnosis. We found that sex and race/ethnicity influence preceding psychiatric conditions and psychiatric treatment use.ConclusionsCareful screening and evaluation to validate diagnoses is important as the presence of certain psychiatric morbidity is common among adolescents with schizophrenia during the prodromal period. Developing acceptable and accessible interventions that will reduce psychiatric hospitalization and residential treatment care and improve care connection for schizophrenia treatment is important to mitigate complexity in treatment for adolescents and reduce cost burden for families and the society. Integrating health claims data in the development of schizophrenia risk conversion models can be useful in effectively predicting ideal timing of tailored interventions for adolescents with preceding psychiatric conditions.https://www.frontiersin.org/article/10.3389/fpsyt.2020.00487/fullschizophreniapreceding psychiatric diagnosespreceding psychiatric treatmentadolescents aged 9–17 yearshealth claims data
spellingShingle Christina D. Kang-Yi
Christina D. Kang-Yi
Brian Chao
Shelly Teng
Jill Locke
David S. Mandell
David S. Mandell
Yin-Ling Irene Wong
C. Neill Epperson
Psychiatric Diagnoses and Treatment Preceding Schizophrenia in Adolescents Aged 9–17 Years
Frontiers in Psychiatry
schizophrenia
preceding psychiatric diagnoses
preceding psychiatric treatment
adolescents aged 9–17 years
health claims data
title Psychiatric Diagnoses and Treatment Preceding Schizophrenia in Adolescents Aged 9–17 Years
title_full Psychiatric Diagnoses and Treatment Preceding Schizophrenia in Adolescents Aged 9–17 Years
title_fullStr Psychiatric Diagnoses and Treatment Preceding Schizophrenia in Adolescents Aged 9–17 Years
title_full_unstemmed Psychiatric Diagnoses and Treatment Preceding Schizophrenia in Adolescents Aged 9–17 Years
title_short Psychiatric Diagnoses and Treatment Preceding Schizophrenia in Adolescents Aged 9–17 Years
title_sort psychiatric diagnoses and treatment preceding schizophrenia in adolescents aged 9 17 years
topic schizophrenia
preceding psychiatric diagnoses
preceding psychiatric treatment
adolescents aged 9–17 years
health claims data
url https://www.frontiersin.org/article/10.3389/fpsyt.2020.00487/full
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