Bronchoalveolar-Lavage-Derived Fibroblast Cell Lines Provide Tools for Investigating Various Interstitial Lung Diseases

Bronchoalveolar-Lavage-Derived Fibroblast Cell Lines Provide Tools for Investigating Various Interstitial Lung Diseases

Bronchoalveolar lavage (BAL) is an important diagnostic and research tool for the investigation of various lung diseases. In addition to inflammatory and epithelial cells, BAL fluid may contain a small number of stromal cells, such as fibroblasts. During the past 30 years, a number of research group...

Full description

Bibliographic Details
Main Authors:	Siri Lehtonen, Riitta Kaarteenaho
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Series:	Cells
Subjects:	idiopathic pulmonary fibrosis BAL-derived cell culture fibroblast myofibroblast
Online Access:	https://www.mdpi.com/2073-4409/11/14/2226

Similar Items

Bronchoalveolar-Lavage-Derived Fibroblast Cell Line (B-LSDM7) as a New Protocol for Investigating the Mechanisms of Idiopathic Pulmonary Fibrosis
by: Laura Bergantini, et al.
Published: (2022-04-01)

Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway
by: Zhen Li, et al.
Published: (2022-03-01)

Albendazole ameliorates aerobic glycolysis in myofibroblasts to reverse pulmonary fibrosis
by: Chenxi Zeng, et al.
Published: (2024-10-01)

Vincristine Promotes Transdifferentiation of Fibroblasts Into Myofibroblasts via P38 and ERK Signal Pathways
by: Hui Xu, et al.
Published: (2022-05-01)

Cromolyn sodium and masitinib combination inhibits fibroblast‐myofibroblast transition and exerts additive cell‐protective and antioxidant effects on a bleomycin‐induced in vitro fibrosis model
by: Azize Yasemin Göksu, et al.
Published: (2024-10-01)

NHLRC2 expression is increased in idiopathic pulmonary fibrosis
by: Mervi Kreus, et al.
Published: (2022-08-01)

Interstitial Macrophages Lead Early Stages of Bleomycin-Induced Lung Fibrosis and Induce Fibroblasts Activation
by: Sofia Libório-Ramos, et al.
Published: (2023-01-01)

SAFETY OF BRONCHOALVEOLAR LAVAGE IN HEMATOLOGICAL PATIENTS WITH THROMBOCYTOPENIA – A RETROSPECTIVE COHORT STUDY
by: Ivan GUR, et al.
Published: (2024-01-01)

Interstitial lung diseases with progressive pulmonary fibrosis: pathogenetic features and approaches to therapy
by: N. A. Kuzubova, et al.
Published: (2020-11-01)

Inhibition of the SET8 Pathway Ameliorates Lung Fibrosis Even Through Fibroblast Dedifferentiation
by: Keita Ugai, et al.
Published: (2020-08-01)

Ferroptosis-Related Genes in Bronchoalveolar Lavage Fluid Serves as Prognostic Biomarkers for Idiopathic Pulmonary Fibrosis
by: Meng Li, et al.
Published: (2021-10-01)

FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis
by: Hamza M Al‐Tamari, et al.
Published: (2017-12-01)

Usefulness of FAPα assessment in bronchoalveolar lavage as a marker of fibrogenesis: results of a preclinical study and first report in patients with idiopathic pulmonary fibrosis
by: Philomène Lavis, et al.
Published: (2023-10-01)

Prognostic Function and Immunologic Landscape of a Predictive Model Based on Five Senescence-Related Genes in IPF Bronchoalveolar Lavage Fluid
by: Cheng Zhong, et al.
Published: (2024-06-01)

Canadian Contributions in Fibroblast Biology
by: Danah S. Al-Hattab, et al.
Published: (2022-07-01)

Human lung fibroblast-to-myofibroblast transformation is not driven by an LDH5-dependent metabolic shift towards aerobic glycolysis
by: Eva Schruf, et al.
Published: (2019-05-01)

Re-hospitalisation predicts poor prognosis after acute exacerbation of interstitial lung disease
by: Johanna Salonen, et al.
Published: (2023-07-01)

Properties and Functions of Fibroblasts and Myofibroblasts in Myocardial Infarction
by: Harikrishnan Venugopal, et al.
Published: (2022-04-01)

Blockade of Sialylation with Decrease in Polysialic Acid Levels Counteracts Transforming Growth Factor β1-Induced Skin Fibroblast-to-Myofibroblast Transition
by: Bianca Saveria Fioretto, et al.
Published: (2024-06-01)

Neutrophils and Lymphocytes: Yin and Yang of Lung Fibrosis and Patient Outcome in Diffuse Interstitial Lung Diseases
by: Erika M. Novoa-Bolivar, et al.
Published: (2024-10-01)

Editorial: Pulmonary fibrosis and lung carcinogenesis: do myofibroblasts and cancer-associated fibroblasts share a common identity?
by: Daniela de Totero, et al.
Published: (2024-03-01)

Dipeptidyl peptidase 4 expression is not associated with an activated fibroblast phenotype in idiopathic pulmonary fibrosis
by: Måns Kadefors, et al.
Published: (2022-08-01)

Emerging roles of non-coding RNAs in fibroblast to myofibroblast transition and fibrotic diseases
by: Xuewu Xing, et al.
Published: (2024-07-01)

Deciphering the age-dependent changes of pulmonary fibroblasts in mice by single-cell transcriptomics
by: Rundong Wu, et al.
Published: (2023-11-01)

Histone methyltransferase KMT2A promotes pulmonary fibrogenesis via targeting pro‐fibrotic factor PU.1 in fibroblasts
by: Wenting Lyu, et al.
Published: (2025-02-01)

Bronchoalveolar lavage fluid polymerase chain reaction for invasive pulmonary aspergillosis among high-risk patients: a diagnostic meta-analysis
by: Yinling Han, et al.
Published: (2023-02-01)

LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation
by: Jian Sun, et al.
Published: (2022-09-01)

Regulation of Cardiac Fibroblast GLS1 Expression by Scleraxis
by: Sikta Chattopadhyaya, et al.
Published: (2022-04-01)

Inhalation of itraconazole mitigates bleomycin-induced lung fibrosis via regulating SPP1 and C3 signaling pathway pivotal in the interaction between phagocytic macrophages and diseased fibroblasts
by: Caizhe Pan, et al.
Published: (2024-11-01)

Dexmedetomidine alleviates pulmonary fibrosis through the ADORA2B-Mediated MAPK signaling pathway
by: Xiaofan Lai, et al.
Published: (2023-08-01)

Different Staining Methods in Diagnosing Lophomonas blattarum in Bronchoalveolar Lavage Samples
by: Fariba Berenji, et al.
Published: (2021-10-01)

Cardiac Fibrosis and Fibroblasts
by: Hitoshi Kurose
Published: (2021-07-01)

Regulation of myofibroblast dedifferentiation in pulmonary fibrosis
by: Xuetao Ju, et al.
Published: (2024-07-01)

CVD and COVID-19: Emerging Roles of Cardiac Fibroblasts and Myofibroblasts
by: Laxmansa C. Katwa, et al.
Published: (2022-04-01)

Complex Relationship Between Cardiac Fibroblasts and Cardiomyocytes in Health and Disease
by: Caitlin Hall, et al.
Published: (2021-03-01)

Granulocyte colony-stimulating factor in bronchoalveolar lavage fluid is a potential biomarker for prognostic prediction of idiopathic pulmonary fibrosis
by: Jong-Uk Lee, et al.
Published: (2022-09-01)

Comparative Analysis of Gene Expression in Fibroblastic Foci in Patients with Idiopathic Pulmonary Fibrosis and Pulmonary Sarcoidosis
by: Jan C. Kamp, et al.
Published: (2022-02-01)

Fibroblast activation protein is a cellular marker of fibrotic activity in canine idiopathic pulmonary fibrosis
by: Elodie Rizzoli, et al.
Published: (2024-07-01)

Molecular Detection of Pneumocystis jirovecii in the Bronchoalveolar Lavage Samples in Patients with Various Pulmonary Disorders(Original Article)
by: Narges Chitsaz, et al.
Published: (2023-12-01)

Bronchoalveolar Lavage Cytology in Severe Equine Asthma: Cytocentrifugated versus Sediment Smear Preparations
by: Maria Morini, et al.
Published: (2023-08-01)