Astrocyte-specific disruption of SynCAM1 signaling results in ADHD-like behavioral manifestations.

Astrocyte-specific disruption of SynCAM1 signaling results in ADHD-like behavioral manifestations.

SynCAM1 is an adhesion molecule involved in synaptic differentiation and organization. SynCAM1 is also expressed in astroglial cells where it mediates astrocyte-to astrocyte and glial-neuronal adhesive communication. In astrocytes, SynCAM1 is functionally linked to erbB4 receptors, which are involve...

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Bibliographic Details
Main Authors: Ursula S Sandau, Zefora Alderman, Gabriel Corfas, Sergio R Ojeda, Jacob Raber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3340339?pdf=render

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