Astrocyte-specific disruption of SynCAM1 signaling results in ADHD-like behavioral manifestations.
SynCAM1 is an adhesion molecule involved in synaptic differentiation and organization. SynCAM1 is also expressed in astroglial cells where it mediates astrocyte-to astrocyte and glial-neuronal adhesive communication. In astrocytes, SynCAM1 is functionally linked to erbB4 receptors, which are involve...
| Auteurs principaux: | , , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
Public Library of Science (PLoS)
2012-01-01
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| Collection: | PLoS ONE |
| Accès en ligne: | http://europepmc.org/articles/PMC3340339?pdf=render |