Treatment of chronic non-infectious uveitis and scleritis
Ocular inflammations such as uveitis and scleritis can lead to significant visual impairment if not treated properly. To limit potentially sight-threatening complications, good control of the inflammation in the acute phase is necessary. Corticosteroids have been the mainstay of ocular therapies f...
| প্রধান লেখক: | , , |
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| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
| প্রকাশিত: |
SMW supporting association (Trägerverein Swiss Medical Weekly SMW)
2019-03-01
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| মালা: | Swiss Medical Weekly |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://www.smw.ch/index.php/smw/article/view/2583 |
| _version_ | 1826996717684260864 |
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| author | Daniele C. Rossi Camillo Ribi Yan Guex-Crosier |
| author_facet | Daniele C. Rossi Camillo Ribi Yan Guex-Crosier |
| author_sort | Daniele C. Rossi |
| collection | DOAJ |
| description |
Ocular inflammations such as uveitis and scleritis can lead to significant visual impairment if not treated properly. To limit potentially sight-threatening complications, good control of the inflammation in the acute phase is necessary. Corticosteroids have been the mainstay of ocular therapies for many years, but high doses of corticosteroids, which are required to maintain quiescence in severe uveitis, can be associated with many systemic and ocular complications. In order to limit steroid side-effects, classic immunosuppressant and immunobiologic agents have been widely used as steroid-sparing agents. In this review, we summarise the immunosuppressive drug therapy utilised in the treatment of ocular inflammatory diseases.
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| first_indexed | 2024-04-11T12:11:57Z |
| format | Article |
| id | doaj.art-a3e13a79a06d4a0a8205853f0c7f33b0 |
| institution | Directory Open Access Journal |
| issn | 1424-3997 |
| language | English |
| last_indexed | 2025-02-18T09:50:07Z |
| publishDate | 2019-03-01 |
| publisher | SMW supporting association (Trägerverein Swiss Medical Weekly SMW) |
| record_format | Article |
| series | Swiss Medical Weekly |
| spelling | doaj.art-a3e13a79a06d4a0a8205853f0c7f33b02024-11-02T11:53:27ZengSMW supporting association (Trägerverein Swiss Medical Weekly SMW)Swiss Medical Weekly1424-39972019-03-01149091010.4414/smw.2019.20025Treatment of chronic non-infectious uveitis and scleritisDaniele C. Rossi0Camillo Ribi1Yan Guex-Crosier2Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, Ophthalmology Department, University of Lausanne, SwitzerlandDivision of Immunology and Allergy, Centre Hospitalier Universitaire Vaudois CHUV, Lausanne, SwitzerlandJules-Gonin Eye Hospital, Fondation Asile des Aveugles, Ophthalmology Department, University of Lausanne, Switzerland Ocular inflammations such as uveitis and scleritis can lead to significant visual impairment if not treated properly. To limit potentially sight-threatening complications, good control of the inflammation in the acute phase is necessary. Corticosteroids have been the mainstay of ocular therapies for many years, but high doses of corticosteroids, which are required to maintain quiescence in severe uveitis, can be associated with many systemic and ocular complications. In order to limit steroid side-effects, classic immunosuppressant and immunobiologic agents have been widely used as steroid-sparing agents. In this review, we summarise the immunosuppressive drug therapy utilised in the treatment of ocular inflammatory diseases. https://www.smw.ch/index.php/smw/article/view/2583anti-TNF agentsazathioprinebiological therapyimmunosuppressive agentsmethotrexatemycophenolate mofetil |
| spellingShingle | Daniele C. Rossi Camillo Ribi Yan Guex-Crosier Treatment of chronic non-infectious uveitis and scleritis Swiss Medical Weekly anti-TNF agents azathioprine biological therapy immunosuppressive agents methotrexate mycophenolate mofetil |
| title | Treatment of chronic non-infectious uveitis and scleritis |
| title_full | Treatment of chronic non-infectious uveitis and scleritis |
| title_fullStr | Treatment of chronic non-infectious uveitis and scleritis |
| title_full_unstemmed | Treatment of chronic non-infectious uveitis and scleritis |
| title_short | Treatment of chronic non-infectious uveitis and scleritis |
| title_sort | treatment of chronic non infectious uveitis and scleritis |
| topic | anti-TNF agents azathioprine biological therapy immunosuppressive agents methotrexate mycophenolate mofetil |
| url | https://www.smw.ch/index.php/smw/article/view/2583 |
| work_keys_str_mv | AT danielecrossi treatmentofchronicnoninfectiousuveitisandscleritis AT camilloribi treatmentofchronicnoninfectiousuveitisandscleritis AT yanguexcrosier treatmentofchronicnoninfectiousuveitisandscleritis |