UBE2T regulates epithelial–mesenchymal transition through the PI3K-AKT pathway and plays a carcinogenic role in ovarian cancer

UBE2T regulates epithelial–mesenchymal transition through the PI3K-AKT pathway and plays a carcinogenic role in ovarian cancer

Abstract Background Ubiquitin-binding enzyme E2T (UBE2T), a member of the E2 family of the ubiquitin–proteasome pathway, is associated with tumorigenesis of varioustumours; however, its role and mechanism in ovarian cancer remain unclear. Results Our study revealed that UBE2T is highly expressed in...

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Bibliographic Details
Main Authors: Ping Cui, Hao Li, Can Wang, Yuan Liu, Mengjun Zhang, Yue Yin, Zhenxing Sun, Yiru Wang, Xiuwei Chen
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Journal of Ovarian Research
Subjects:
Epithelial–mesenchymal transition
Ubiquitin-binding enzyme E2T
Tumorigenesis
Ovarian cancer
Online Access:https://doi.org/10.1186/s13048-022-01034-9

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