Spatial memory deficiency early in 6xTg Alzheimer’s disease mouse model
Abstract Alzheimer’s disease (AD) is mainly characterized by the deposition of extracellular amyloid plaques and intracellular accumulation of neurofibrillary tangles (NFTs). While the recent 5xFAD AD mouse model exhibits many AD-related phenotypes and a relatively early and aggressive amyloid β pro...
Main Authors: | Shinwoo Kang, Jinho Kim, Keun-A Chang |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-79344-5 |
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