Maprotiline Prevents Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats

Pulmonary arterial hypertension (PAH) is a progressive disease caused by increased pulmonary artery pressure and pulmonary vascular resistance, eventually leading to right heart failure until death. Soluble guanylate cyclase (sGC) has been regarded as an attractive drug target in treating PAH. In th...

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Détails bibliographiques
Auteurs principaux: Yi Tong, Qian Jiao, Yuanru Liu, Jiankun Lv, Rui Wang, Lili Zhu
Format: Article
Langue:English
Publié: Frontiers Media S.A. 2018-09-01
Collection:Frontiers in Pharmacology
Sujets:
Accès en ligne:https://www.frontiersin.org/article/10.3389/fphar.2018.01032/full