Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression
Di Domenico et al., provide a comprehensive assessment of DNA methylation in a large cohort of pancreatic neuroendocrine tumors. This work provides new insights into the epigenetic heterogeneity of the disease and cellular basis.
Main Authors: | Annunziata Di Domenico, Christodoulos P. Pipinikas, Renaud S. Maire, Konstantin Bräutigam, Cedric Simillion, Matthias S. Dettmer, Erik Vassella, Chrissie Thirlwell, Aurel Perren, Ilaria Marinoni |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-12-01
|
Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-020-01479-y |
Similar Items
-
Distinct mechanisms of hypoglycaemia in patients with somatostatin‐secreting neuroendocrine tumours
by: Peter Wiesli, et al.
Published: (2019-10-01) -
Additional malignancies in patients with neuroendocrine tumours: analysis of the SwissNET registry
by: Attila Kollár, et al.
Published: (2016-11-01) -
EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs)
by: Simon Leonhard April-Monn, et al.
Published: (2021-10-01) -
Effect of epigenetic treatment on SST2 expression in neuroendocrine tumour patients
by: Julie Refardt, et al.
Published: (2022-07-01) -
Gastroenteropancreatic neuroendocrine tumours.
by: Modlin, I, et al.
Published: (2008)