Inhibition of hypothalamic leukemia inhibitory factor exacerbates diet-induced obesity phenotype

Inhibition of hypothalamic leukemia inhibitory factor exacerbates diet-induced obesity phenotype

Abstract Background The consumption of large amounts of dietary fats can trigger an inflammatory response in the hypothalamus and contribute to the dysfunctional control of caloric intake and energy expenditure commonly present in obesity. The objective of this study was to identify chemokine-relate...

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Bibliographic Details
Main Authors: Milena Fioravante, Bruna Bombassaro, Albina F. Ramalho, Nathalia R. Dragano, Joseane Morari, Carina Solon, Natalia Tobar, Celso D. Ramos, Licio A. Velloso
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Journal of Neuroinflammation
Subjects:
Diabetes
Glucose
Insulin
Adipose tissue
Inflammation
Online Access:http://link.springer.com/article/10.1186/s12974-017-0956-9

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