Detection and localisation of PrP(Sc) in the liver of sheep infected with scrapie and bovine spongiform encephalopathy.

Detection and localisation of PrP(Sc) in the liver of sheep infected with scrapie and bovine spongiform encephalopathy.

Prions are largely contained within the nervous and lymphoid tissue of transmissible spongiform encephalopathy (TSE) infected animals. However, following advances in diagnostic sensitivity, PrP(Sc), a marker for prion disease, can now be located in a wide range of viscera and body fluids including m...

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Bibliographic Details
Main Authors: Sally J Everest, Andrew M Ramsay, Melanie J Chaplin, Sharon Everitt, Michael J Stack, Michael H Neale, Martin Jeffrey, S Jo Moore, Susan J Bellworthy, Linda A Terry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3093390?pdf=render

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