Multivariate Chemometric Comparison of Forced Degradation and Electrochemical Oxidation LC–MS Profiles of Maraviroc

Multivariate Chemometric Comparison of Forced Degradation and Electrochemical Oxidation LC–MS Profiles of Maraviroc

In this study, nine forced degradation products of maraviroc were found using chemometric analysis. This antiretroviral drug was subjected to photolytic, oxidative, as well as neutral, basic and acidic hydrolysis stress conditions. Additionally, its electrochemical transformation on platinum, gold a...

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Bibliographic Details
Main Authors: Michał Wroński, Jakub Trawiński, Łukasz Komsta, Robert Skibiński
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
chemometrics
Q-TOF
mass spectrometry
UHPLC
photodegradation
degradation studies
Online Access:https://www.mdpi.com/1420-3049/28/3/1195

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