Comparing ability and norm-referenced scores as clinical trial outcomes for neurodevelopmental disabilities: a simulation study

Comparing ability and norm-referenced scores as clinical trial outcomes for neurodevelopmental disabilities: a simulation study

Abstract Background For genetic conditions associated with neurodevelopmental disorder (GCAND), developmental domains such as motor ability, thinking and learning, social abilities, and communication are potential intervention targets. Performance on measures of developmental concepts can be express...

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Bibliographic Details
Main Authors: Cristan Farmer, Audrey Thurm, Jesse D. Troy, Aaron J. Kaat
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
Ability score
Growth scale value
Rasch analysis
Item response theory
Neurodevelopmental disability
Rare genetic condition
Online Access:https://doi.org/10.1186/s11689-022-09474-6

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