Multifaceted analysis of cross-tissue transcriptomes reveals phenotype–endotype associations in atopic dermatitis

Multifaceted analysis of cross-tissue transcriptomes reveals phenotype–endotype associations in atopic dermatitis

Abstract Atopic dermatitis (AD) is a skin disease that is heterogeneous both in terms of clinical manifestations and molecular profiles. It is increasingly recognized that AD is a systemic rather than a local disease and should be assessed in the context of whole-body pathophysiology. Here we show,...

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Main Authors: Aiko Sekita, Hiroshi Kawasaki, Ayano Fukushima-Nomura, Kiyoshi Yashiro, Keiji Tanese, Susumu Toshima, Koichi Ashizaki, Tomohiro Miyai, Junshi Yazaki, Atsuo Kobayashi, Shinichi Namba, Tatsuhiko Naito, Qingbo S. Wang, Eiryo Kawakami, Jun Seita, Osamu Ohara, Kazuhiro Sakurada, Yukinori Okada, Masayuki Amagai, Haruhiko Koseki
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41857-8

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