Improving Industrially Relevant Phenotypic Traits by Engineering Chromosome Copy Number in Saccharomyces pastorianus

Improving Industrially Relevant Phenotypic Traits by Engineering Chromosome Copy Number in Saccharomyces pastorianus

The lager-brewing yeast Saccharomyces pastorianus is a hybrid between S. cerevisiae and S. eubayanus with an exceptional degree of aneuploidy. While chromosome copy number variation (CCNV) is present in many industrial Saccharomyces strains and has been linked to various industrially-relevant traits...

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Bibliographic Details
Main Authors: Arthur R. Gorter de Vries, Ewout Knibbe, Roderick van Roosmalen, Marcel van den Broek, Pilar de la Torre Cortés, Stephanie F. O’Herne, Pascal A. Vijverberg, Anissa el Masoudi, Nick Brouwers, Jack T. Pronk, Jean-Marc G. Daran
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Genetics
Subjects:
Saccharomyces pastorianus
chromosome missegregation
chromosome copy number stability
strain engineering
lager beer brewing
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00518/full

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