Peroxisome proliferator-activated receptor-γ as the gatekeeper of tight junction in Clostridioides difficile infection

Peroxisome proliferator-activated receptor-γ as the gatekeeper of tight junction in Clostridioides difficile infection

Clostridioides difficile is a major causative pathogen of nosocomial antibiotic-associated diarrhea and severe colitis. Despite the use of vancomycin and fidaxomicin as standard drugs for the treatment of C. difficile infection (CDI), clinical relapse rates remain high. Therefore, new alternative th...

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Bibliographic Details
Main Authors:	Yi-Hsin Lai, Tai-Chieh Wu, Bo-Yang Tsai, Yuan-Pin Hung, Hsiao-Ju Lin, Yau-Sheng Tsai, Wen-Chien Ko, Pei-Jane Tsai
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Series:	Frontiers in Microbiology
Subjects:	Clostridioides difficile peroxisome proliferator-activated receptor-γ tight junction occludin pioglitazone
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2022.986457/full

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