Natural products against inflammation and atherosclerosis: Targeting on gut microbiota
The gut microbiota (GM) has become recognized as a crucial element in preserving human fitness and influencing disease consequences. Commensal and pathogenic gut microorganisms are correlated with pathological progress in atherosclerosis (AS). GM may thus be a promising therapeutic target for AS. Na...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-12-01
|
| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2022.997056/full |
| _version_ | 1797987943309115392 |
|---|---|
| author | Bing Deng Liyu Tao Yiru Wang |
| author_facet | Bing Deng Liyu Tao Yiru Wang |
| author_sort | Bing Deng |
| collection | DOAJ |
| description | The gut microbiota (GM) has become recognized as a crucial element in preserving human fitness and influencing disease consequences. Commensal and pathogenic gut microorganisms are correlated with pathological progress in atherosclerosis (AS). GM may thus be a promising therapeutic target for AS. Natural products with cardioprotective qualities might improve the inflammation of AS by modulating the GM ecosystem, opening new avenues for researches and therapies. However, it is unclear what components of natural products are useful and what the actual mechanisms are. In this review, we have summarized the natural products relieving inflammation of AS by regulating the GM balance and active metabolites produced by GM. |
| first_indexed | 2024-04-11T07:54:56Z |
| format | Article |
| id | doaj.art-a4018663149248f7ace934ee875bd45f |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-04-11T07:54:56Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-a4018663149248f7ace934ee875bd45f2022-12-22T04:35:57ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2022-12-011310.3389/fmicb.2022.997056997056Natural products against inflammation and atherosclerosis: Targeting on gut microbiotaBing Deng0Liyu Tao1Yiru Wang2Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaShuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaThe gut microbiota (GM) has become recognized as a crucial element in preserving human fitness and influencing disease consequences. Commensal and pathogenic gut microorganisms are correlated with pathological progress in atherosclerosis (AS). GM may thus be a promising therapeutic target for AS. Natural products with cardioprotective qualities might improve the inflammation of AS by modulating the GM ecosystem, opening new avenues for researches and therapies. However, it is unclear what components of natural products are useful and what the actual mechanisms are. In this review, we have summarized the natural products relieving inflammation of AS by regulating the GM balance and active metabolites produced by GM.https://www.frontiersin.org/articles/10.3389/fmicb.2022.997056/fullgut microbiotaatherosclerosisinflammationnatural productsimmune |
| spellingShingle | Bing Deng Liyu Tao Yiru Wang Natural products against inflammation and atherosclerosis: Targeting on gut microbiota Frontiers in Microbiology gut microbiota atherosclerosis inflammation natural products immune |
| title | Natural products against inflammation and atherosclerosis: Targeting on gut microbiota |
| title_full | Natural products against inflammation and atherosclerosis: Targeting on gut microbiota |
| title_fullStr | Natural products against inflammation and atherosclerosis: Targeting on gut microbiota |
| title_full_unstemmed | Natural products against inflammation and atherosclerosis: Targeting on gut microbiota |
| title_short | Natural products against inflammation and atherosclerosis: Targeting on gut microbiota |
| title_sort | natural products against inflammation and atherosclerosis targeting on gut microbiota |
| topic | gut microbiota atherosclerosis inflammation natural products immune |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2022.997056/full |
| work_keys_str_mv | AT bingdeng naturalproductsagainstinflammationandatherosclerosistargetingongutmicrobiota AT liyutao naturalproductsagainstinflammationandatherosclerosistargetingongutmicrobiota AT yiruwang naturalproductsagainstinflammationandatherosclerosistargetingongutmicrobiota |