Clinical Laboratory Changes in Children with Hematuric Form of Chronic Glomerulonephritis Following Chronic Epstein — Barr Virus Infection
The purpose is to study the clinical laboratory features of hematuric form of chronic glomerulonephritis (HFCGN) in children with chronic Epstein — Barr virus infection (EBVI). 110 children with HFCGN at the age of 3–17 years were examined. For EBVI detection IgM, IgG EA, IgG VCA, IgG EBNA were det...
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| Format: | Article |
| Language: | English |
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Zaslavsky O.Yu.
2012-11-01
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| Series: | Zdorovʹe Rebenka |
| Subjects: | |
| Online Access: | http://childshealth.zaslavsky.com.ua/article/view/192316 |
| _version_ | 1798017123457433600 |
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| author | Ye.N. Tolchennikova |
| author_facet | Ye.N. Tolchennikova |
| author_sort | Ye.N. Tolchennikova |
| collection | DOAJ |
| description | The purpose is to study the clinical laboratory features of hematuric form of chronic glomerulonephritis (HFCGN) in children with chronic Epstein — Barr virus infection (EBVI). 110 children with HFCGN at the age of 3–17 years were examined. For EBVI detection IgM, IgG EA, IgG VCA, IgG EBNA were determined by method of immune-enzyme analysis, viral antigen — by method of polymerase chain reaction in blood, saliva, urine. Chronic EBVI was detected in 54 (49.1 %) of children with HFCGN. Mean age of HFCGN onset in group of children with EBVI was 5.57 ± 0.50 years against 8.02 ± 0.46 years in children without EBVI. Common clinical features in patients with chronic EBVI were higher frequency of significant erythrocyturia, presence of macrohematuria and tubular disorders, systemic lymphadenopathy, hepatosplenomegaly, asthenic syndrome, leukopenia, lymphocytosis, monocytosis. The severity of erythrocyturia and presence of tubular disorders depended on the degree of EBVI activity. |
| first_indexed | 2024-04-11T16:01:42Z |
| format | Article |
| id | doaj.art-a40a27b477f64c75b70747b3126ebed6 |
| institution | Directory Open Access Journal |
| issn | 2224-0551 2307-1168 |
| language | English |
| last_indexed | 2024-04-11T16:01:42Z |
| publishDate | 2012-11-01 |
| publisher | Zaslavsky O.Yu. |
| record_format | Article |
| series | Zdorovʹe Rebenka |
| spelling | doaj.art-a40a27b477f64c75b70747b3126ebed62022-12-22T04:15:01ZengZaslavsky O.Yu.Zdorovʹe Rebenka2224-05512307-11682012-11-0108.43778010.22141/2224-0551.0.8.43.2012.192316192316Clinical Laboratory Changes in Children with Hematuric Form of Chronic Glomerulonephritis Following Chronic Epstein — Barr Virus InfectionYe.N. Tolchennikova0Regional Children’s Clinical Hospital, Donetsk, UkraineThe purpose is to study the clinical laboratory features of hematuric form of chronic glomerulonephritis (HFCGN) in children with chronic Epstein — Barr virus infection (EBVI). 110 children with HFCGN at the age of 3–17 years were examined. For EBVI detection IgM, IgG EA, IgG VCA, IgG EBNA were determined by method of immune-enzyme analysis, viral antigen — by method of polymerase chain reaction in blood, saliva, urine. Chronic EBVI was detected in 54 (49.1 %) of children with HFCGN. Mean age of HFCGN onset in group of children with EBVI was 5.57 ± 0.50 years against 8.02 ± 0.46 years in children without EBVI. Common clinical features in patients with chronic EBVI were higher frequency of significant erythrocyturia, presence of macrohematuria and tubular disorders, systemic lymphadenopathy, hepatosplenomegaly, asthenic syndrome, leukopenia, lymphocytosis, monocytosis. The severity of erythrocyturia and presence of tubular disorders depended on the degree of EBVI activity.http://childshealth.zaslavsky.com.ua/article/view/192316chronic glomerulonephritis, hematuric form, children, epstein — barr virus infection |
| spellingShingle | Ye.N. Tolchennikova Clinical Laboratory Changes in Children with Hematuric Form of Chronic Glomerulonephritis Following Chronic Epstein — Barr Virus Infection Zdorovʹe Rebenka chronic glomerulonephritis, hematuric form, children, epstein — barr virus infection |
| title | Clinical Laboratory Changes in Children with Hematuric Form of Chronic Glomerulonephritis Following Chronic Epstein — Barr Virus Infection |
| title_full | Clinical Laboratory Changes in Children with Hematuric Form of Chronic Glomerulonephritis Following Chronic Epstein — Barr Virus Infection |
| title_fullStr | Clinical Laboratory Changes in Children with Hematuric Form of Chronic Glomerulonephritis Following Chronic Epstein — Barr Virus Infection |
| title_full_unstemmed | Clinical Laboratory Changes in Children with Hematuric Form of Chronic Glomerulonephritis Following Chronic Epstein — Barr Virus Infection |
| title_short | Clinical Laboratory Changes in Children with Hematuric Form of Chronic Glomerulonephritis Following Chronic Epstein — Barr Virus Infection |
| title_sort | clinical laboratory changes in children with hematuric form of chronic glomerulonephritis following chronic epstein barr virus infection |
| topic | chronic glomerulonephritis, hematuric form, children, epstein — barr virus infection |
| url | http://childshealth.zaslavsky.com.ua/article/view/192316 |
| work_keys_str_mv | AT yentolchennikova clinicallaboratorychangesinchildrenwithhematuricformofchronicglomerulonephritisfollowingchronicepsteinbarrvirusinfection |