Drug-Resistant Malaria Parasites Introduced into Madagascar from Comoros Islands

Drug-Resistant Malaria Parasites Introduced into Madagascar from Comoros Islands

To determine risk for drug-resistant malaria parasites entering Madagascar from Comoros Islands, we screened travelers. For the 141 Plasmodium falciparum isolates detected by real-time PCR, frequency of mutant alleles of genes associated with resistance to chloroquine and pyrimethamine was high. Int...

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Bibliographic Details
Main Authors: Didier Ménard, Armand Eugène Randrianarivo-Solofoniaina, Bedja Said Ahmed, Martial Jahevitra, Landy Valérie Andriantsoanirina, Justin Ranjalahy Rasolofomanana, Léon Paul Rabarijaona
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2007-11-01
Series:Emerging Infectious Diseases
Subjects:
malaria
Plasmodium falciparum
drug resistance
spread resistance
chloroquine
sulfadoxine-pyrimethamine
Online Access:https://wwwnc.cdc.gov/eid/article/13/11/07-0235_article
Description
Summary:To determine risk for drug-resistant malaria parasites entering Madagascar from Comoros Islands, we screened travelers. For the 141 Plasmodium falciparum isolates detected by real-time PCR, frequency of mutant alleles of genes associated with resistance to chloroquine and pyrimethamine was high. International-level antimalarial policy and a regional antimalarial forum are needed.
ISSN:1080-6040
1080-6059

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