Longitudinal Assessment of Tau-Associated Pathology by <sup>18</sup>F-THK5351 PET Imaging: A Histological, Biochemical, and Behavioral Study

Longitudinal Assessment of Tau-Associated Pathology by <sup>18</sup>F-THK5351 PET Imaging: A Histological, Biochemical, and Behavioral Study

Several common and debilitating neurodegenerative disorders are characterized by the intracellular accumulation of neurofibrillary tangles (NFTs), which are composed of hyperphosphorylated tau protein. In Alzheimer’s disease (AD), NFTs are accompanied by extracellular amyloid-beta (Aβ), but primary...

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Bibliographic Details
Main Authors:	Ines Moreno-Gonzalez, George A. Edwards, Omar Hasan, Nazaret Gamez, Jonathan E. Schulz, Juan Jose Fernandez-Valenzuela, Antonia Gutierrez, Claudio Soto, Paul E. Schulz
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Series:	Diagnostics
Subjects:	PET imaging Tau THK5351 tracer biomarker histological assessment
Online Access:	https://www.mdpi.com/2075-4418/11/10/1874

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