Long-lived pancreatic ductal adenocarcinoma slice cultures enable precise study of the immune microenvironment

Long-lived pancreatic ductal adenocarcinoma slice cultures enable precise study of the immune microenvironment

Pancreatic ductal adenocarcinoma (PDA) remains a deadly disease that is rarely cured, despite many recent successes with immunotherapy for other malignancies. As the human disease is heavily infiltrated by effector T cells, we postulated that accurately modeling the PDA immune microenvironment would...

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Bibliographic Details
Main Authors: Xiuyun Jiang, Y. David Seo, Jae Hyuck Chang, Andrew Coveler, Eslam N. Nigjeh, Sheng Pan, Florencia Jalikis, Raymond S. Yeung, Ian N. Crispe, Venu G. Pillarisetty
Format: Article
Language:English
Published: Taylor & Francis Group 2017-07-01
Series:OncoImmunology
Subjects:
immune cells
model
pancreatic ductal adenocarcinoma
pda
slice culture
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1333210

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