Remote Monitoring of Visual Function in Patients with Maculopathy: The Aphelion Study
Abstract Introduction Remote monitoring of vision, using tools such as the shape discrimination hyperacuity (SDH) test, can detect disease activity in patients with maculopathy. We determined the in-clinic accuracy and repeatability of three myVisionTrack expanded version (mVTx) tests for self-testi...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Adis, Springer Healthcare
2023-11-01
|
| Series: | Ophthalmology and Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s40123-023-00854-2 |
| _version_ | 1827382357717417984 |
|---|---|
| author | Anthony Joseph Mark Bullimore Faye Drawnel Marco Miranda Zoe Morgan Yi-Zhong Wang |
| author_facet | Anthony Joseph Mark Bullimore Faye Drawnel Marco Miranda Zoe Morgan Yi-Zhong Wang |
| author_sort | Anthony Joseph |
| collection | DOAJ |
| description | Abstract Introduction Remote monitoring of vision, using tools such as the shape discrimination hyperacuity (SDH) test, can detect disease activity in patients with maculopathy. We determined the in-clinic accuracy and repeatability of three myVisionTrack expanded version (mVTx) tests for self-testing of visual acuity (VA) and contrast sensitivity. Methods Aphelion, a single-arm, prospective study conducted at two sites in the USA, included adults with any maculopathy and a baseline VA of 0.7 log of minimum angle of resolution (logMAR) (Snellen 20/100) or better. Participants completed the mVTx tests (tumbling E, Landolt C, contrast sensitivity, and SDH) and standard clinical tests (near and distance Early Treatment Diabetic Retinopathy Study [ETDRS] charts and the Pelli–Robson contrast sensitivity chart). Test–retest repeatability and agreement between the mVTx tests and the corresponding clinical test were assessed by Bland–Altman analyses. Participants also completed a usability survey. Results The mean age of the 122 participants was 67 years. The most common diagnosis was age-related macular degeneration (42% of patients). The tumbling E test had a test–retest 95% limit of agreement (LoA) of ± 0.18 logMAR; the Landolt C test, ± 0.23 logMAR; the SDH test, ± 0.24 logMAR; and the contrast sensitivity test, ± 0.32 log contrast threshold (logCT). Compared with the distance ETDRS chart, the LoA was ± 0.35 logMAR for the tumbling E test (mean difference, − 0.07 logMAR) and ± 0.39 logMAR for the Landolt C test (mean difference, 0.03 logMAR). For the contrast sensitivity test, the LoA compared with the Pelli–Robson chart was ± 0.30 logCT (mean difference, − 0.25 logCT). Most participants (85%) reported that they learned the tests quickly. The tumbling E test scored the highest on ease of use. Conclusion The mVTx tests of VA are accurate and repeatable, supporting their potential use alongside the SDH test to detect disease progression remotely between clinic visits. |
| first_indexed | 2024-03-08T14:19:24Z |
| format | Article |
| id | doaj.art-a410eb91d17a46ccab9ae0bb3cd54cb5 |
| institution | Directory Open Access Journal |
| issn | 2193-8245 2193-6528 |
| language | English |
| last_indexed | 2024-03-08T14:19:24Z |
| publishDate | 2023-11-01 |
| publisher | Adis, Springer Healthcare |
| record_format | Article |
| series | Ophthalmology and Therapy |
| spelling | doaj.art-a410eb91d17a46ccab9ae0bb3cd54cb52024-01-14T12:14:25ZengAdis, Springer HealthcareOphthalmology and Therapy2193-82452193-65282023-11-0113140942210.1007/s40123-023-00854-2Remote Monitoring of Visual Function in Patients with Maculopathy: The Aphelion StudyAnthony Joseph0Mark Bullimore1Faye Drawnel2Marco Miranda3Zoe Morgan4Yi-Zhong Wang5Retina AssociatesUniversity of Houston College of OptometryF. Hoffmann-La Roche AGRoche Products, Ltd.F. Hoffmann-La Roche AGRetina Foundation of the SouthwestAbstract Introduction Remote monitoring of vision, using tools such as the shape discrimination hyperacuity (SDH) test, can detect disease activity in patients with maculopathy. We determined the in-clinic accuracy and repeatability of three myVisionTrack expanded version (mVTx) tests for self-testing of visual acuity (VA) and contrast sensitivity. Methods Aphelion, a single-arm, prospective study conducted at two sites in the USA, included adults with any maculopathy and a baseline VA of 0.7 log of minimum angle of resolution (logMAR) (Snellen 20/100) or better. Participants completed the mVTx tests (tumbling E, Landolt C, contrast sensitivity, and SDH) and standard clinical tests (near and distance Early Treatment Diabetic Retinopathy Study [ETDRS] charts and the Pelli–Robson contrast sensitivity chart). Test–retest repeatability and agreement between the mVTx tests and the corresponding clinical test were assessed by Bland–Altman analyses. Participants also completed a usability survey. Results The mean age of the 122 participants was 67 years. The most common diagnosis was age-related macular degeneration (42% of patients). The tumbling E test had a test–retest 95% limit of agreement (LoA) of ± 0.18 logMAR; the Landolt C test, ± 0.23 logMAR; the SDH test, ± 0.24 logMAR; and the contrast sensitivity test, ± 0.32 log contrast threshold (logCT). Compared with the distance ETDRS chart, the LoA was ± 0.35 logMAR for the tumbling E test (mean difference, − 0.07 logMAR) and ± 0.39 logMAR for the Landolt C test (mean difference, 0.03 logMAR). For the contrast sensitivity test, the LoA compared with the Pelli–Robson chart was ± 0.30 logCT (mean difference, − 0.25 logCT). Most participants (85%) reported that they learned the tests quickly. The tumbling E test scored the highest on ease of use. Conclusion The mVTx tests of VA are accurate and repeatable, supporting their potential use alongside the SDH test to detect disease progression remotely between clinic visits.https://doi.org/10.1007/s40123-023-00854-2Contrast sensitivityHyperacuityMaculopathyRemote monitoringVisual acuitySmartphone application |
| spellingShingle | Anthony Joseph Mark Bullimore Faye Drawnel Marco Miranda Zoe Morgan Yi-Zhong Wang Remote Monitoring of Visual Function in Patients with Maculopathy: The Aphelion Study Ophthalmology and Therapy Contrast sensitivity Hyperacuity Maculopathy Remote monitoring Visual acuity Smartphone application |
| title | Remote Monitoring of Visual Function in Patients with Maculopathy: The Aphelion Study |
| title_full | Remote Monitoring of Visual Function in Patients with Maculopathy: The Aphelion Study |
| title_fullStr | Remote Monitoring of Visual Function in Patients with Maculopathy: The Aphelion Study |
| title_full_unstemmed | Remote Monitoring of Visual Function in Patients with Maculopathy: The Aphelion Study |
| title_short | Remote Monitoring of Visual Function in Patients with Maculopathy: The Aphelion Study |
| title_sort | remote monitoring of visual function in patients with maculopathy the aphelion study |
| topic | Contrast sensitivity Hyperacuity Maculopathy Remote monitoring Visual acuity Smartphone application |
| url | https://doi.org/10.1007/s40123-023-00854-2 |
| work_keys_str_mv | AT anthonyjoseph remotemonitoringofvisualfunctioninpatientswithmaculopathytheaphelionstudy AT markbullimore remotemonitoringofvisualfunctioninpatientswithmaculopathytheaphelionstudy AT fayedrawnel remotemonitoringofvisualfunctioninpatientswithmaculopathytheaphelionstudy AT marcomiranda remotemonitoringofvisualfunctioninpatientswithmaculopathytheaphelionstudy AT zoemorgan remotemonitoringofvisualfunctioninpatientswithmaculopathytheaphelionstudy AT yizhongwang remotemonitoringofvisualfunctioninpatientswithmaculopathytheaphelionstudy |