Tissue Expression of Programmed Cell Death 1 Ligand1 (PD-L1) in Biopsies of Transplant Livers of Pediatric Patients as a Possible Marker of Acute Cellular Rejection

Tissue Expression of Programmed Cell Death 1 Ligand1 (PD-L1) in Biopsies of Transplant Livers of Pediatric Patients as a Possible Marker of Acute Cellular Rejection

Introduction: Preclinical models have demonstrated that PD-1 and its ligand programmed death ligand1 (PD-L1) play significant roles in both graft induction and the maintenance of immune tolerance. It has also been suggested that PD-L1 tissue expression may predict graft rejection; however, the avail...

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Bibliographic Details
Main Authors: Sylwia Szymanska, Malgorzata Markiewicz-Kijewska, Michal Pyzlak, Agnieszka Karkucinska-Wienckowska, Mateusz Ciopinski, Piotr Czubkowski, Piotr Kaliciński
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Journal of Clinical Medicine
Subjects:
pediatric liver transplantation
liver biopsy
PD-L1
ACR
immune tolerance
Online Access:https://www.mdpi.com/2077-0383/12/13/4269

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https://www.mdpi.com/2077-0383/12/13/4269

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