Production of vaccines for treatment of infectious diseases by transgenic plants
Since the first pathogen antigen was expressed in transgenic plants with the aim of producing edible vaccine in early 1990s, transgenic plants have become a well-established expression system for production of alternative vaccines against various human and animal infectious diseases. The main focus...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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University of Ljubljana Press (Založba Univerze v Ljubljani)
2016-04-01
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| Series: | Acta Agriculturae Slovenica |
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| Online Access: | https://journals.uni-lj.si/aas/article/view/12645 |
| _version_ | 1797697984727613440 |
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| author | Kristina LEDL Zlata LUTHAR |
| author_facet | Kristina LEDL Zlata LUTHAR |
| author_sort | Kristina LEDL |
| collection | DOAJ |
| description |
Since the first pathogen antigen was expressed in transgenic plants with the aim of producing edible vaccine in early 1990s, transgenic plants have become a well-established expression system for production of alternative vaccines against various human and animal infectious diseases. The main focus of plant expression systems in the last five years has been on improving expression of well-studied antigens such as porcine reproductive and respiratory syndrome (PRRSV), bovine viral diarrhea disease virus (BVDV), footh and mouth disease virus (FMDV), hepatitis B surface antigen (HBsAg), rabies G protein, rotavirus, Newcastle disease virus (NDV), Norwalk virus capsid protein (NVCP), avian influenza virus H5N1, Escherichia coli heat-labile enterotoxin subunit B (LT-B), cholera toxin B (CT-B), human immunodeficiency virus (HIV), artherosclerosis, ebola and anthrax. Significant increases in expression have been obtained using improved expression vectors, different plant species and transformation methods.
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| first_indexed | 2024-03-12T03:47:42Z |
| format | Article |
| id | doaj.art-a4269692444a47bdaecd41efb1c47348 |
| institution | Directory Open Access Journal |
| issn | 1854-1941 |
| language | English |
| last_indexed | 2024-03-12T03:47:42Z |
| publishDate | 2016-04-01 |
| publisher | University of Ljubljana Press (Založba Univerze v Ljubljani) |
| record_format | Article |
| series | Acta Agriculturae Slovenica |
| spelling | doaj.art-a4269692444a47bdaecd41efb1c473482023-09-03T12:36:04ZengUniversity of Ljubljana Press (Založba Univerze v Ljubljani)Acta Agriculturae Slovenica1854-19412016-04-01107110.14720/aas.2016.107.1.1919037Production of vaccines for treatment of infectious diseases by transgenic plantsKristina LEDL0Zlata LUTHAR1Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1000 LjubljanaBiotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana Since the first pathogen antigen was expressed in transgenic plants with the aim of producing edible vaccine in early 1990s, transgenic plants have become a well-established expression system for production of alternative vaccines against various human and animal infectious diseases. The main focus of plant expression systems in the last five years has been on improving expression of well-studied antigens such as porcine reproductive and respiratory syndrome (PRRSV), bovine viral diarrhea disease virus (BVDV), footh and mouth disease virus (FMDV), hepatitis B surface antigen (HBsAg), rabies G protein, rotavirus, Newcastle disease virus (NDV), Norwalk virus capsid protein (NVCP), avian influenza virus H5N1, Escherichia coli heat-labile enterotoxin subunit B (LT-B), cholera toxin B (CT-B), human immunodeficiency virus (HIV), artherosclerosis, ebola and anthrax. Significant increases in expression have been obtained using improved expression vectors, different plant species and transformation methods. https://journals.uni-lj.si/aas/article/view/12645transgenic plantsvaccine productionrecombinant proteinsantibodiesinfectious diseasesrisk assessment |
| spellingShingle | Kristina LEDL Zlata LUTHAR Production of vaccines for treatment of infectious diseases by transgenic plants Acta Agriculturae Slovenica transgenic plants vaccine production recombinant proteins antibodies infectious diseases risk assessment |
| title | Production of vaccines for treatment of infectious diseases by transgenic plants |
| title_full | Production of vaccines for treatment of infectious diseases by transgenic plants |
| title_fullStr | Production of vaccines for treatment of infectious diseases by transgenic plants |
| title_full_unstemmed | Production of vaccines for treatment of infectious diseases by transgenic plants |
| title_short | Production of vaccines for treatment of infectious diseases by transgenic plants |
| title_sort | production of vaccines for treatment of infectious diseases by transgenic plants |
| topic | transgenic plants vaccine production recombinant proteins antibodies infectious diseases risk assessment |
| url | https://journals.uni-lj.si/aas/article/view/12645 |
| work_keys_str_mv | AT kristinaledl productionofvaccinesfortreatmentofinfectiousdiseasesbytransgenicplants AT zlataluthar productionofvaccinesfortreatmentofinfectiousdiseasesbytransgenicplants |