Yin and yang of cannabinoid CB1 receptor: CB1 deletion in immune cells causes exacerbation while deletion in non-immune cells attenuates obesity

Yin and yang of cannabinoid CB1 receptor: CB1 deletion in immune cells causes exacerbation while deletion in non-immune cells attenuates obesity

Summary: While blockade of cannabinoid receptor 1 (CB1) has been shown to attenuate diet-induced obesity (DIO), its relative role in different cell types has not been tested. The current study investigated the role of CB1 in immune vs non-immune cells during DIO by generating radiation-induced bone...

Full description

Bibliographic Details
Main Authors: Kathryn Miranda, William Becker, Philip B. Busbee, Nicholas Dopkins, Osama A. Abdulla, Yin Zhong, Jiajia Zhang, Mitzi Nagarkatti, Prakash S. Nagarkatti
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:iScience
Subjects:
Immunology
Hematology
Human metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222012664

Similar Items

Similar Items