Amphiregulin Exerts Proangiogenic Effects in Developing Murine Lungs

Amphiregulin Exerts Proangiogenic Effects in Developing Murine Lungs

Interrupted lung angiogenesis is a hallmark of bronchopulmonary dysplasia (BPD); however, druggable targets that can rescue this phenotype remain elusive. Thus, our investigation focused on amphiregulin (Areg), a growth factor that mediates cellular proliferation, differentiation, migration, surviva...

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Bibliographic Details
Main Authors: Shyam Thapa, Nithyapriya Shankar, Amrit Kumar Shrestha, Monish Civunigunta, Amos S. Gaikwad, Binoy Shivanna
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Antioxidants
Subjects:
angiogenesis
amphiregulin
fetal murine lung endothelial cells
hyperoxia
bronchopulmonary dysplasia
Online Access:https://www.mdpi.com/2076-3921/13/1/78

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