Oncogenic K-ras Induces Mitochondrial OPA3 Expression to Promote Energy Metabolism in Pancreatic Cancer Cells
K-ras (Kirsten ras GTPase) mutations are oncogenic events frequently observed in many cancer types especially in pancreatic cancer. Although mitochondrial dysfunction has been associated with K-ras mutation, the molecular mechanisms by which K-ras impacts mitochondria and maintains metabolic homeost...
Main Authors: | Ning Meng, Christophe Glorieux, Yanyu Zhang, Liyun Liang, Peiting Zeng, Wenhua Lu, Peng Huang |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-12-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/12/1/65 |
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