Autophagy receptor optineurin promotes autophagosome formation by potentiating LC3-II production and phagophore maturation

Autophagy is an essential physiological process that maintains cellular homeostasis by eliminating harmful protein aggregates, damaged organelles and certain pathogens through lysosomal degradation. During autophagy specialized structures, known as autophagosomes are formed that recruit the cargo th...

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Bibliographic Details
Main Authors: Megha Bansal, Shivranjani C Moharir, Ghanshyam Swarup
Format: Article
Language:English
Published: Taylor & Francis Group 2018-03-01
Series:Communicative & Integrative Biology
Subjects:
Online Access:http://dx.doi.org/10.1080/19420889.2018.1467189