CD74-dependent Deregulation of the Tumor Suppressor Scribble in Human Epithelial and Breast Cancer Cells

CD74-dependent Deregulation of the Tumor Suppressor Scribble in Human Epithelial and Breast Cancer Cells

The γ subunit of the major histocompatibility complex (MHC) class II complex, CD74, is overexpressed in a significant proportion of metastatic breast tumors, but the mechanistic foundation and biologic significance of this phenomenon are not fully understood. Here, we show that when CD74 is overexpr...

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Bibliographic Details
Main Authors: Gergana Metodieva, Naiara Correa Nogueira-de-Souza, Christina Greenwood, Khalid Al-Janabi, Lin Leng, Richard Bucala, Metodi V Metodiev
Format: Article
Language:English
Published: Elsevier 2013-06-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861380139X

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