Factors affecting drug-induced liver injury: antithyroid drugs as instances
Methimazole and propylthiouracil have been used in the management of hyperthyroidism for more than half a century. However, hepatotoxicity is one of the most deleterious side effects associated with these medications. The mechanism(s) of hepatic injury induced by antithyroid agents is not fully reco...
Main Authors: | Reza Heidari, Hossein Niknahad, Akram Jamshidzadeh, Narges Abdoli |
---|---|
Format: | Article |
Language: | English |
Published: |
Korean Association for the Study of the Liver
2014-09-01
|
Series: | Clinical and Molecular Hepatology |
Subjects: | |
Online Access: | http://e-cmh.org/upload/pdf/cmh-20-237.pdf |
Similar Items
-
The Postulated Hepatotoxic Metabolite of Methimazole Causes Mitochondrial Dysfunction and Energy Metabolism Disturbances in Liver
by: Hossein Niknahad 1,2, Akram Jamshidzadeh 1,2, Reza Heidari 1 * , Narges Abdoli 3, Mohammad Mehdi Ommati 4, Faezeh Jafari 2, Mahdi Zarei 2, Behnam Asadi 2
Published: (2016-12-01) -
The Hepatoprotection Provided by Taurine and Glycine against Antineoplastic Drugs Induced Liver Injury in an Ex Vivo Model of Normothermic Recirculating Isolated Perfused Rat Liver
by: Reza Heidari, et al.
Published: (2016-02-01) -
The Hepatoprotection Provided by Taurine and Glycine against Antineoplastic Drugs Induced Liver Injury in an Ex Vivo Model of Normothermic Recirculating Isolated Perfused Rat Liver
by: Reza Heidari, et al.
Published: (2016-03-01) -
The Hepatoprotective Role of Thiol Reductants against Mitoxantrone-Induced Liver Injury
by: Hossein Niknahad, et al.
Published: (2017-06-01) -
The Hepatoprotective Role of Thiol Reductants against Mitoxantrone-Induced Liver Injury
by: Hossein Niknahad, et al.
Published: (2017-05-01)