Host-Defense Peptides Caerin 1.1 and 1.9 Stimulate TNF-Alpha-Dependent Apoptotic Signals in Human Cervical Cancer HeLa Cells

Host-Defense Peptides Caerin 1.1 and 1.9 Stimulate TNF-Alpha-Dependent Apoptotic Signals in Human Cervical Cancer HeLa Cells

Host defense caerin 1.1 and 1.9 peptides, isolated from the glandular secretion of Australian tree frogs, the genus Litoria, have been previously shown to have multiple biological activities, including the inhibition of human papillomavirus (HPV) 16 early protein E7 transformed murine as well as hum...

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Main Authors: Guoying Ni, Shu Chen, Mo Chen, Jialing Wu, Binbin Yang, Jianwei Yuan, Shelley F. Walton, Hejie Li, Ming Q. Wei, Yuejian Wang, Guoqiang Chen, Xiaosong Liu, Tianfang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
caerin peptide
HeLa cell
apoptosis
TNF-α signaling pathway
TMT labeling
proteomics
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00676/full

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