Spectral characteristics of the hippocampal LFP during contextual fear conditioning
Objective: The hippocampus has an important role in the acquisitionand recall of aversive memories. The objective of this study was toinvestigate the relationship among hippocampal rhythms. Methods:Microeletrodes arrays were implanted in the hippocampus of Wistarrats. The animals were trained and te...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Instituto Israelita de Ensino e Pesquisa Albert Einstein
2012-06-01
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| Series: | Einstein (São Paulo) |
| Subjects: | |
| Online Access: | http://apps.einstein.br/revista/arquivos/PDF/2242-140-144.pdf |
| _version_ | 1811194170585382912 |
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| author | Birajara Soares Machado Ana Carolina Bione Kunicki Edgard Morya Koichi Sameshima |
| author_facet | Birajara Soares Machado Ana Carolina Bione Kunicki Edgard Morya Koichi Sameshima |
| author_sort | Birajara Soares Machado |
| collection | DOAJ |
| description | Objective: The hippocampus has an important role in the acquisitionand recall of aversive memories. The objective of this study was toinvestigate the relationship among hippocampal rhythms. Methods:Microeletrodes arrays were implanted in the hippocampus of Wistarrats. The animals were trained and tested in a contextual fearconditioning task. The training consisted in applying shocks in thelegs. The memory test was performed 1 day (recent memory) or 18days (remote memory) after training. We proposed a measure basedon the FFT power spectrum, denominated “delta-theta ratio”, tocharacterize the different behaviors (active exploration and freezing)and the memories types. Results: The delta-theta ratio was able todistinguish recent and remote memories. In this study, the ratio forthe 18-day group was smaller than for the 1-day group. Moreover,this measure was useful to distinguish the different behavior states– active exploration and freezing. Conclusions: The results suggestdelta-theta oscillations could reflect the demands on informationprocessing during recent and remote memory recalls. |
| first_indexed | 2024-04-12T00:21:32Z |
| format | Article |
| id | doaj.art-a44329630d474c3997463117678cad6e |
| institution | Directory Open Access Journal |
| issn | 1679-4508 |
| language | English |
| last_indexed | 2024-04-12T00:21:32Z |
| publishDate | 2012-06-01 |
| publisher | Instituto Israelita de Ensino e Pesquisa Albert Einstein |
| record_format | Article |
| series | Einstein (São Paulo) |
| spelling | doaj.art-a44329630d474c3997463117678cad6e2022-12-22T03:55:42ZengInstituto Israelita de Ensino e Pesquisa Albert EinsteinEinstein (São Paulo)1679-45082012-06-01102140144Spectral characteristics of the hippocampal LFP during contextual fear conditioningBirajara Soares MachadoAna Carolina Bione KunickiEdgard MoryaKoichi SameshimaObjective: The hippocampus has an important role in the acquisitionand recall of aversive memories. The objective of this study was toinvestigate the relationship among hippocampal rhythms. Methods:Microeletrodes arrays were implanted in the hippocampus of Wistarrats. The animals were trained and tested in a contextual fearconditioning task. The training consisted in applying shocks in thelegs. The memory test was performed 1 day (recent memory) or 18days (remote memory) after training. We proposed a measure basedon the FFT power spectrum, denominated “delta-theta ratio”, tocharacterize the different behaviors (active exploration and freezing)and the memories types. Results: The delta-theta ratio was able todistinguish recent and remote memories. In this study, the ratio forthe 18-day group was smaller than for the 1-day group. Moreover,this measure was useful to distinguish the different behavior states– active exploration and freezing. Conclusions: The results suggestdelta-theta oscillations could reflect the demands on informationprocessing during recent and remote memory recalls.http://apps.einstein.br/revista/arquivos/PDF/2242-140-144.pdfHippocampusMemoryFear/physiologyAmnesia retrograde |
| spellingShingle | Birajara Soares Machado Ana Carolina Bione Kunicki Edgard Morya Koichi Sameshima Spectral characteristics of the hippocampal LFP during contextual fear conditioning Einstein (São Paulo) Hippocampus Memory Fear/physiology Amnesia retrograde |
| title | Spectral characteristics of the hippocampal LFP during contextual fear conditioning |
| title_full | Spectral characteristics of the hippocampal LFP during contextual fear conditioning |
| title_fullStr | Spectral characteristics of the hippocampal LFP during contextual fear conditioning |
| title_full_unstemmed | Spectral characteristics of the hippocampal LFP during contextual fear conditioning |
| title_short | Spectral characteristics of the hippocampal LFP during contextual fear conditioning |
| title_sort | spectral characteristics of the hippocampal lfp during contextual fear conditioning |
| topic | Hippocampus Memory Fear/physiology Amnesia retrograde |
| url | http://apps.einstein.br/revista/arquivos/PDF/2242-140-144.pdf |
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