Extracellular Nucleophosmin Is Increased in Psoriasis and Correlates With the Determinants of Cardiovascular Diseases

Extracellular Nucleophosmin Is Increased in Psoriasis and Correlates With the Determinants of Cardiovascular Diseases

We previously showed that genotoxic stress induced an active extracellular release of nucleophosmin (NPM) in human cardiac mesenchymal progenitor cells, and that serum deprivation provokes NPM secretion from human endothelial cells, eliciting inflammation via nuclear factor kappa B (NF-kB) transcrip...

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Bibliographic Details
Main Authors: Marco D'Agostino, Sara Beji, Sara Sileno, Daniela Lulli, Laura Mercurio, Stefania Madonna, Corrado Cirielli, Sabatino Pallotta, Cristina Albanesi, Maurizio C. Capogrossi, Daniele Avitabile, Guido Melillo, Alessandra Magenta
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
alarmin
inflammation
microRNAs
psoriasis
atherosclerosis
cardiovascular diseases
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.867813/full

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