Addressing variability in iPSC-derived models of human disease: guidelines to promote reproducibility
Induced pluripotent stem cell (iPSC) technologies have provided in vitro models of inaccessible human cell types, yielding new insights into disease mechanisms especially for neurological disorders. However, without due consideration, the thousands of new human iPSC lines generated in the past decad...
Main Authors: | Viola Volpato, Caleb Webber |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2020-01-01
|
Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/13/1/dmm042317 |
Similar Items
-
iPSC-Derived Cardiomyocytes in Inherited Cardiac Arrhythmias: Pathomechanistic Discovery and Drug Development
by: Eline Simons, et al.
Published: (2023-01-01) -
Comparison of gene expression between human and mouse iPSC-derived cardiomyocytes for stem cell therapies of cardiovascular defects via bioinformatic analysis
by: Ryan Bellman, et al.
Published: (2023-03-01) -
Low-Intensity Pulsed Ultrasound Promotes Osteogenic Potential of iPSC-Derived MSCs but Fails to Simplify the iPSC-EB-MSC Differentiation Process
by: Ziyi Hua, et al.
Published: (2022-05-01) -
Comparison of two protocols for the generation of iPSC-derived human astrocytes
by: Patrycja Mulica, et al.
Published: (2023-09-01) -
iPSC for modeling neurodegenerative disorders
by: Valeria Valadez-Barba, et al.
Published: (2020-12-01)