The Relationship of Myometrial Invasion Between Other Prognostic Parameters in Endometrial Cancer
Objective: The aim of this study is to investigate the relationship between deep myometrial invasion and other prognostic factors in endometrial cancer. Recurrence rates, disease free survival and overall survival rates were evaluated in endometrial cancer patients with MI>50%. Sudy Design: A to...
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| Format: | Article |
| Language: | English |
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Medical Network
2017-12-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
| Subjects: | |
| Online Access: | http://gorm.com.tr/index.php/GORM/article/view/648 |
| _version_ | 1828028912191406080 |
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| author | Mehmet Sait Bakır Ali Emre Tahaoğlu Emre Erdoğdu Cem Dane |
| author_facet | Mehmet Sait Bakır Ali Emre Tahaoğlu Emre Erdoğdu Cem Dane |
| author_sort | Mehmet Sait Bakır |
| collection | DOAJ |
| description | Objective: The aim of this study is to investigate the relationship between deep myometrial invasion and other prognostic factors in endometrial cancer. Recurrence rates, disease free survival and overall survival rates were evaluated in endometrial cancer patients with MI>50%.
Sudy Design: A total of 132 patients with endometrial cancer who underwent surgical treatment between 2001 and 2011 were identified. Demographic, clinicopathological, surgical/adjuvant treatment and follow-up data were extracted.
Results: Pelvic lymph node invasion ratio was 28,9% and para-aortic lymph node invasion ratio was 15,5% in patients with myometrial invasion is greater than 50%. Other prognostic factors especially lympho-vascular space invasion and pelvic/para-aortic lymph node metastasis were significantly higher when myometrial invasion is above 50% and also there was significant difference in recurrence rates, overall survival and disease free survival rates between patients with superficial and deep myometrial invasion (p<0.05).
Conclusion: Myometrial invasion is an important prognostic parameter and can be determined intraoperatively to decide whether to perform pelvic and para-aortic lymph node dissection. |
| first_indexed | 2024-04-10T14:01:17Z |
| format | Article |
| id | doaj.art-a44733c84d2a4da884d7867e7482e3a1 |
| institution | Directory Open Access Journal |
| issn | 1300-4751 |
| language | English |
| last_indexed | 2024-04-10T14:01:17Z |
| publishDate | 2017-12-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj.art-a44733c84d2a4da884d7867e7482e3a12023-02-15T16:10:15ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512017-12-0123315816210.21613/GORM.2016.648585The Relationship of Myometrial Invasion Between Other Prognostic Parameters in Endometrial CancerMehmet Sait Bakır0Ali Emre Tahaoğlu1Emre Erdoğdu2Cem Dane3Health Sciences University Gazi Yasargil Research and Training Hospital, DiyarbakırHealth Sciences University, Gazi Yasargil Research and Training Hospital, DiyarbakırHealth Sciences University Gazi Yasargil Research and Training Hospital, DiyarbakırHaseki Research and Training Hospital, IstanbulObjective: The aim of this study is to investigate the relationship between deep myometrial invasion and other prognostic factors in endometrial cancer. Recurrence rates, disease free survival and overall survival rates were evaluated in endometrial cancer patients with MI>50%. Sudy Design: A total of 132 patients with endometrial cancer who underwent surgical treatment between 2001 and 2011 were identified. Demographic, clinicopathological, surgical/adjuvant treatment and follow-up data were extracted. Results: Pelvic lymph node invasion ratio was 28,9% and para-aortic lymph node invasion ratio was 15,5% in patients with myometrial invasion is greater than 50%. Other prognostic factors especially lympho-vascular space invasion and pelvic/para-aortic lymph node metastasis were significantly higher when myometrial invasion is above 50% and also there was significant difference in recurrence rates, overall survival and disease free survival rates between patients with superficial and deep myometrial invasion (p<0.05). Conclusion: Myometrial invasion is an important prognostic parameter and can be determined intraoperatively to decide whether to perform pelvic and para-aortic lymph node dissection.http://gorm.com.tr/index.php/GORM/article/view/648Endometrial cancer, Myometrial invasion, Overall survival |
| spellingShingle | Mehmet Sait Bakır Ali Emre Tahaoğlu Emre Erdoğdu Cem Dane The Relationship of Myometrial Invasion Between Other Prognostic Parameters in Endometrial Cancer Gynecology Obstetrics & Reproductive Medicine Endometrial cancer, Myometrial invasion, Overall survival |
| title | The Relationship of Myometrial Invasion Between Other Prognostic Parameters in Endometrial Cancer |
| title_full | The Relationship of Myometrial Invasion Between Other Prognostic Parameters in Endometrial Cancer |
| title_fullStr | The Relationship of Myometrial Invasion Between Other Prognostic Parameters in Endometrial Cancer |
| title_full_unstemmed | The Relationship of Myometrial Invasion Between Other Prognostic Parameters in Endometrial Cancer |
| title_short | The Relationship of Myometrial Invasion Between Other Prognostic Parameters in Endometrial Cancer |
| title_sort | relationship of myometrial invasion between other prognostic parameters in endometrial cancer |
| topic | Endometrial cancer, Myometrial invasion, Overall survival |
| url | http://gorm.com.tr/index.php/GORM/article/view/648 |
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