MODERN APPROACHES TO THE CONTROL OF ACTIVE COMPONENTS OF CHOLERA CHEMICAL VACCINE
The paper considers the requirements to the production of pharmaceutical substances and the current trends in the toxicity assessment of the preparations obtained. The results of research of the use cell cultures for test bioactive substances, including cholera toxin are given. Evaluated are the adv...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
| Subjects: | |
| Online Access: | https://www.pharmjournal.ru/jour/article/view/558 |
| _version_ | 1797875052639682560 |
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| author | A. V. Gaeva O. V. Gromova O. S. Durakov S. V. Generalov O. A. Volokh |
| author_facet | A. V. Gaeva O. V. Gromova O. S. Durakov S. V. Generalov O. A. Volokh |
| author_sort | A. V. Gaeva |
| collection | DOAJ |
| description | The paper considers the requirements to the production of pharmaceutical substances and the current trends in the toxicity assessment of the preparations obtained. The results of research of the use cell cultures for test bioactive substances, including cholera toxin are given. Evaluated are the advantages of in vitro methods application, in particular, continuous cell lines at some stages of cholera chemical vaccine manufacturing. |
| first_indexed | 2024-04-10T01:41:35Z |
| format | Article |
| id | doaj.art-a44bf35b10ac45e88ec31fbd1740a2f7 |
| institution | Directory Open Access Journal |
| issn | 2305-2066 2658-5049 |
| language | Russian |
| last_indexed | 2024-04-10T01:41:35Z |
| publishDate | 2019-01-01 |
| publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
| record_format | Article |
| series | Разработка и регистрация лекарственных средств |
| spelling | doaj.art-a44bf35b10ac45e88ec31fbd1740a2f72023-03-13T09:13:57ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0101152157558MODERN APPROACHES TO THE CONTROL OF ACTIVE COMPONENTS OF CHOLERA CHEMICAL VACCINEA. V. Gaeva0O. V. Gromova1O. S. Durakov2S. V. Generalov3O. A. Volokh4ФКУЗ «Российский научно-исследовательский противочумный институт «Микроб» РоспотребнадзораФКУЗ «Российский научно-исследовательский противочумный институт «Микроб» РоспотребнадзораФКУЗ «Российский научно-исследовательский противочумный институт «Микроб» РоспотребнадзораФКУЗ «Российский научно-исследовательский противочумный институт «Микроб» РоспотребнадзораФКУЗ «Российский научно-исследовательский противочумный институт «Микроб» РоспотребнадзораThe paper considers the requirements to the production of pharmaceutical substances and the current trends in the toxicity assessment of the preparations obtained. The results of research of the use cell cultures for test bioactive substances, including cholera toxin are given. Evaluated are the advantages of in vitro methods application, in particular, continuous cell lines at some stages of cholera chemical vaccine manufacturing.https://www.pharmjournal.ru/jour/article/view/558вакцинытоксигенностькультура клеток |
| spellingShingle | A. V. Gaeva O. V. Gromova O. S. Durakov S. V. Generalov O. A. Volokh MODERN APPROACHES TO THE CONTROL OF ACTIVE COMPONENTS OF CHOLERA CHEMICAL VACCINE Разработка и регистрация лекарственных средств вакцины токсигенность культура клеток |
| title | MODERN APPROACHES TO THE CONTROL OF ACTIVE COMPONENTS OF CHOLERA CHEMICAL VACCINE |
| title_full | MODERN APPROACHES TO THE CONTROL OF ACTIVE COMPONENTS OF CHOLERA CHEMICAL VACCINE |
| title_fullStr | MODERN APPROACHES TO THE CONTROL OF ACTIVE COMPONENTS OF CHOLERA CHEMICAL VACCINE |
| title_full_unstemmed | MODERN APPROACHES TO THE CONTROL OF ACTIVE COMPONENTS OF CHOLERA CHEMICAL VACCINE |
| title_short | MODERN APPROACHES TO THE CONTROL OF ACTIVE COMPONENTS OF CHOLERA CHEMICAL VACCINE |
| title_sort | modern approaches to the control of active components of cholera chemical vaccine |
| topic | вакцины токсигенность культура клеток |
| url | https://www.pharmjournal.ru/jour/article/view/558 |
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