Proteome and phosphoproteome signatures of recurrence for HPV+ head and neck squamous cell carcinoma
Kaneko et al. compare the proteome and phosphoproteome of primary HPV + oropharyngeal squamous cell cancers with tumours that recurred following chemotherapy/radiation. The authors identify signatures of fibrosis, matrix remodeling, and epithelial-mesenchymal transition and reprogrammed cytoskeletal...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-07-01
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| Series: | Communications Medicine |
| Online Access: | https://doi.org/10.1038/s43856-022-00159-8 |
| _version_ | 1828189782287581184 |
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| author | Tomonori Kaneko Peter Y. F. Zeng Xuguang Liu Rober Abdo John W. Barrett Qi Zhang Anthony C. Nichols Shawn Shun-Cheng Li |
| author_facet | Tomonori Kaneko Peter Y. F. Zeng Xuguang Liu Rober Abdo John W. Barrett Qi Zhang Anthony C. Nichols Shawn Shun-Cheng Li |
| author_sort | Tomonori Kaneko |
| collection | DOAJ |
| description | Kaneko et al. compare the proteome and phosphoproteome of primary HPV + oropharyngeal squamous cell cancers with tumours that recurred following chemotherapy/radiation. The authors identify signatures of fibrosis, matrix remodeling, and epithelial-mesenchymal transition and reprogrammed cytoskeletal signalling in recurrent tumours. |
| first_indexed | 2024-04-12T08:11:25Z |
| format | Article |
| id | doaj.art-a44ce57f6a334a38873bee17ae0c6444 |
| institution | Directory Open Access Journal |
| issn | 2730-664X |
| language | English |
| last_indexed | 2024-04-12T08:11:25Z |
| publishDate | 2022-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Medicine |
| spelling | doaj.art-a44ce57f6a334a38873bee17ae0c64442022-12-22T03:40:58ZengNature PortfolioCommunications Medicine2730-664X2022-07-012111510.1038/s43856-022-00159-8Proteome and phosphoproteome signatures of recurrence for HPV+ head and neck squamous cell carcinomaTomonori Kaneko0Peter Y. F. Zeng1Xuguang Liu2Rober Abdo3John W. Barrett4Qi Zhang5Anthony C. Nichols6Shawn Shun-Cheng Li7Department of Biochemistry, Schulich School of Medicine and Dentistry, Western UniversityDepartment of Otolaryngology - Head and Neck Surgery, Schulich School of Medicine and Dentistry, Western UniversityDepartment of Biochemistry, Schulich School of Medicine and Dentistry, Western UniversityDepartment of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western UniversityDepartment of Otolaryngology - Head and Neck Surgery, Schulich School of Medicine and Dentistry, Western UniversityDepartment of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western UniversityDepartment of Otolaryngology - Head and Neck Surgery, Schulich School of Medicine and Dentistry, Western UniversityDepartment of Biochemistry, Schulich School of Medicine and Dentistry, Western UniversityKaneko et al. compare the proteome and phosphoproteome of primary HPV + oropharyngeal squamous cell cancers with tumours that recurred following chemotherapy/radiation. The authors identify signatures of fibrosis, matrix remodeling, and epithelial-mesenchymal transition and reprogrammed cytoskeletal signalling in recurrent tumours.https://doi.org/10.1038/s43856-022-00159-8 |
| spellingShingle | Tomonori Kaneko Peter Y. F. Zeng Xuguang Liu Rober Abdo John W. Barrett Qi Zhang Anthony C. Nichols Shawn Shun-Cheng Li Proteome and phosphoproteome signatures of recurrence for HPV+ head and neck squamous cell carcinoma Communications Medicine |
| title | Proteome and phosphoproteome signatures of recurrence for HPV+ head and neck squamous cell carcinoma |
| title_full | Proteome and phosphoproteome signatures of recurrence for HPV+ head and neck squamous cell carcinoma |
| title_fullStr | Proteome and phosphoproteome signatures of recurrence for HPV+ head and neck squamous cell carcinoma |
| title_full_unstemmed | Proteome and phosphoproteome signatures of recurrence for HPV+ head and neck squamous cell carcinoma |
| title_short | Proteome and phosphoproteome signatures of recurrence for HPV+ head and neck squamous cell carcinoma |
| title_sort | proteome and phosphoproteome signatures of recurrence for hpv head and neck squamous cell carcinoma |
| url | https://doi.org/10.1038/s43856-022-00159-8 |
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