Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa.
For clinicians, Pseudomonas aeruginosa is a nightmare pathogen that is one of the top three causes of opportunistic human infections. Therapy of P. aeruginosa infections is complicated due to its natural high intrinsic resistance to antibiotics. Active efflux and decreased uptake of drugs due to cel...
Main Authors: | Ayssar A Elamin, Susanne Steinicke, Wulf Oehlmann, Yvonne Braun, Hanaa Wanas, Eduard A Shuralev, Carmen Huck, Marko Maringer, Manfred Rohde, Mahavir Singh |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5646862?pdf=render |
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