Characteristics and Clinical Application of Extracellular Vesicle-Derived DNA

Characteristics and Clinical Application of Extracellular Vesicle-Derived DNA

Extracellular vesicles (EVs) carry RNA, proteins, lipids, and diverse biomolecules for intercellular communication. Recent studies have reported that EVs contain double-stranded DNA (dsDNA) and oncogenic mutant DNA. The advantage of EV-derived DNA (EV DNA) over cell-free DNA (cfDNA) is the stability...

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Bibliographic Details
Main Authors: Jae Young Hur, Kye Young Lee
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
extracellular vesicle
exosome
microvesicle
EV DNA
liquid biopsy
next-generation sequencing
Online Access:https://www.mdpi.com/2072-6694/13/15/3827

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