Purulent Hidradenitis. Part I

Until recently, the pathogenesis of purulent hidradenitis was a little- and sporadically studied issue, which invariably created difficulties in the therapeutic treatment of this disease. Its often severe recurrency rate, high incidence and the lack of effective treatment have predetermined the urge...

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Main Authors: A. N. Rodionov, S. V. Skrek, A. V. Sobolev, A. A. Yunovidova, L. R. Chernova, P. Wolkenstein
Format: Article
Language:English
Published: State Scientific Center of Dermatovenereology and Cosmetology 2018-01-01
Series:Vestnik Dermatologii i Venerologii
Subjects:
Online Access:https://www.vestnikdv.ru/jour/article/view/341
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author A. N. Rodionov
S. V. Skrek
A. V. Sobolev
A. A. Yunovidova
L. R. Chernova
P. Wolkenstein
author_facet A. N. Rodionov
S. V. Skrek
A. V. Sobolev
A. A. Yunovidova
L. R. Chernova
P. Wolkenstein
author_sort A. N. Rodionov
collection DOAJ
description Until recently, the pathogenesis of purulent hidradenitis was a little- and sporadically studied issue, which invariably created difficulties in the therapeutic treatment of this disease. Its often severe recurrency rate, high incidence and the lack of effective treatment have predetermined the urgency of the problem and raised the scientific and practical interest in this field among the scientists worldwide. Recent data indicate a significant role of damage-associated molecular patterns (DAMP) and the activation of congenital immunity, associated with Th17 lymphocytes, in the development of inflammatory disease. Likewise, the violation of the transmission of the cellular Notch signaling pathway plays an important role in the development of purulent hidradenitis.
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spelling doaj.art-a452edd0f90b40e2b51b29a50250b7722023-08-02T00:27:09ZengState Scientific Center of Dermatovenereology and CosmetologyVestnik Dermatologii i Venerologii0042-46092313-62942018-01-0105475110.25208/0042-4609-2017-0-5-125-126336Purulent Hidradenitis. Part IA. N. Rodionov0S. V. Skrek1A. V. Sobolev2A. A. Yunovidova3L. R. Chernova4P. Wolkenstein5North-Western State Medical University named after I. I. Mechnikov of the Ministry of Health of Russian Federation, St. PetersburgNorth-Western State Medical University named after I. I. Mechnikov of the Ministry of Health of Russian Federation, St. Petersburg; The Pierre Wolkenstein French Dermatological Clinic, St. PetersburgResearch Institute of Medical Mycology named after P. N. Kashkin, North-Western State Medical University named after I. I. Mechnikov of the Ministry of Health of Russian Federation, St. PetersburgThe Pierre Wolkenstein French Dermatological Clinic, St. PetersburgThe Pierre Wolkenstein French Dermatological Clinic, St. PetersburgDermatological Service of the Henri Mondor University Hospital, CréteilUntil recently, the pathogenesis of purulent hidradenitis was a little- and sporadically studied issue, which invariably created difficulties in the therapeutic treatment of this disease. Its often severe recurrency rate, high incidence and the lack of effective treatment have predetermined the urgency of the problem and raised the scientific and practical interest in this field among the scientists worldwide. Recent data indicate a significant role of damage-associated molecular patterns (DAMP) and the activation of congenital immunity, associated with Th17 lymphocytes, in the development of inflammatory disease. Likewise, the violation of the transmission of the cellular Notch signaling pathway plays an important role in the development of purulent hidradenitis.https://www.vestnikdv.ru/jour/article/view/341purulent hidradenitisnotch signaling pathwayth17 cellsurulent hidradenitisnotch signaling pathwayth17 cellsȗ-secretase secretase
spellingShingle A. N. Rodionov
S. V. Skrek
A. V. Sobolev
A. A. Yunovidova
L. R. Chernova
P. Wolkenstein
Purulent Hidradenitis. Part I
Vestnik Dermatologii i Venerologii
purulent hidradenitis
notch signaling pathway
th17 cells
urulent hidradenitis
notch signaling pathway
th17 cells
ȗ-secretase secretase
title Purulent Hidradenitis. Part I
title_full Purulent Hidradenitis. Part I
title_fullStr Purulent Hidradenitis. Part I
title_full_unstemmed Purulent Hidradenitis. Part I
title_short Purulent Hidradenitis. Part I
title_sort purulent hidradenitis part i
topic purulent hidradenitis
notch signaling pathway
th17 cells
urulent hidradenitis
notch signaling pathway
th17 cells
ȗ-secretase secretase
url https://www.vestnikdv.ru/jour/article/view/341
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