The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer

Background & Objective: Prostate cancer is a compound condition in which gene expression has altered. Several surveys have revealed that genetic components have been involved in prostate cancer progression. Findings proposed that they can modify a noteworthy portion of disposing of elements, whi...

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Main Authors: parisa Fouman Ajirloo, arezo zaree, saeid ghorbian
Format: Article
Language:English
Published: Fasa University of Medical Sciences 2019-04-01
Series:Journal of Advanced Biomedical Sciences
Subjects:
Online Access:http://jabs.fums.ac.ir/article-1-1805-en.pdf
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author parisa Fouman Ajirloo
arezo zaree
saeid ghorbian
author_facet parisa Fouman Ajirloo
arezo zaree
saeid ghorbian
author_sort parisa Fouman Ajirloo
collection DOAJ
description Background & Objective: Prostate cancer is a compound condition in which gene expression has altered. Several surveys have revealed that genetic components have been involved in prostate cancer progression. Findings proposed that they can modify a noteworthy portion of disposing of elements, which is associated to the developing prostate cancer in protein coding sequences. The purpose of this research was to indicate that there are many long non-coding RNAs with over 200 nucleotides length found in the human genome, which showed a significant role in the pathogenesis of prostate cancer.  Conclusion: The role of LncRNAs as tumor suppressors or oncogenes has been demonstrated in several types of cancers, including prostate cancer. Recent investigations have disclosed that LncRNAs transcripts play a pivotal role in the tumorigenesis.
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spelling doaj.art-a4566ac5710f43c7b06f82481578db272023-09-20T21:26:04ZengFasa University of Medical SciencesJournal of Advanced Biomedical Sciences2228-51052783-15232019-04-019111871199The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancerparisa Fouman Ajirloo0arezo zaree1saeid ghorbian2 Departman of Molecular Genetic, Ahar Branch, Islamic Azad University, Ahar, Iran Departman of Molecular Genetic, Ahar Branch, Islamic Azad University, Ahar, Iran Departman of Molecular Genetic, Ahar Branch, Islamic Azad University, Ahar, Iran Background & Objective: Prostate cancer is a compound condition in which gene expression has altered. Several surveys have revealed that genetic components have been involved in prostate cancer progression. Findings proposed that they can modify a noteworthy portion of disposing of elements, which is associated to the developing prostate cancer in protein coding sequences. The purpose of this research was to indicate that there are many long non-coding RNAs with over 200 nucleotides length found in the human genome, which showed a significant role in the pathogenesis of prostate cancer.  Conclusion: The role of LncRNAs as tumor suppressors or oncogenes has been demonstrated in several types of cancers, including prostate cancer. Recent investigations have disclosed that LncRNAs transcripts play a pivotal role in the tumorigenesis.http://jabs.fums.ac.ir/article-1-1805-en.pdfprostate cancerlong non-coding rnalncrna
spellingShingle parisa Fouman Ajirloo
arezo zaree
saeid ghorbian
The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer
Journal of Advanced Biomedical Sciences
prostate cancer
long non-coding rna
lncrna
title The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer
title_full The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer
title_fullStr The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer
title_full_unstemmed The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer
title_short The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer
title_sort roles of long non coding rnas lncrna in prostate cancer
topic prostate cancer
long non-coding rna
lncrna
url http://jabs.fums.ac.ir/article-1-1805-en.pdf
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