The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer
Background & Objective: Prostate cancer is a compound condition in which gene expression has altered. Several surveys have revealed that genetic components have been involved in prostate cancer progression. Findings proposed that they can modify a noteworthy portion of disposing of elements, whi...
Main Authors: | , , |
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Format: | Article |
Language: | English |
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Fasa University of Medical Sciences
2019-04-01
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Series: | Journal of Advanced Biomedical Sciences |
Subjects: | |
Online Access: | http://jabs.fums.ac.ir/article-1-1805-en.pdf |
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author | parisa Fouman Ajirloo arezo zaree saeid ghorbian |
author_facet | parisa Fouman Ajirloo arezo zaree saeid ghorbian |
author_sort | parisa Fouman Ajirloo |
collection | DOAJ |
description | Background & Objective: Prostate cancer is a compound condition in which gene expression has altered. Several surveys have revealed that genetic components have been involved in prostate cancer progression. Findings proposed that they can modify a noteworthy portion of disposing of elements, which is associated to the developing prostate cancer in protein coding sequences. The purpose of this research was to indicate that there are many long non-coding RNAs with over 200 nucleotides length found in the human genome, which showed a significant role in the pathogenesis of prostate cancer.
Conclusion: The role of LncRNAs as tumor suppressors or oncogenes has been demonstrated in several types of cancers, including prostate cancer. Recent investigations have disclosed that LncRNAs transcripts play a pivotal role in the tumorigenesis. |
first_indexed | 2024-03-11T23:17:47Z |
format | Article |
id | doaj.art-a4566ac5710f43c7b06f82481578db27 |
institution | Directory Open Access Journal |
issn | 2228-5105 2783-1523 |
language | English |
last_indexed | 2024-03-11T23:17:47Z |
publishDate | 2019-04-01 |
publisher | Fasa University of Medical Sciences |
record_format | Article |
series | Journal of Advanced Biomedical Sciences |
spelling | doaj.art-a4566ac5710f43c7b06f82481578db272023-09-20T21:26:04ZengFasa University of Medical SciencesJournal of Advanced Biomedical Sciences2228-51052783-15232019-04-019111871199The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancerparisa Fouman Ajirloo0arezo zaree1saeid ghorbian2 Departman of Molecular Genetic, Ahar Branch, Islamic Azad University, Ahar, Iran Departman of Molecular Genetic, Ahar Branch, Islamic Azad University, Ahar, Iran Departman of Molecular Genetic, Ahar Branch, Islamic Azad University, Ahar, Iran Background & Objective: Prostate cancer is a compound condition in which gene expression has altered. Several surveys have revealed that genetic components have been involved in prostate cancer progression. Findings proposed that they can modify a noteworthy portion of disposing of elements, which is associated to the developing prostate cancer in protein coding sequences. The purpose of this research was to indicate that there are many long non-coding RNAs with over 200 nucleotides length found in the human genome, which showed a significant role in the pathogenesis of prostate cancer. Conclusion: The role of LncRNAs as tumor suppressors or oncogenes has been demonstrated in several types of cancers, including prostate cancer. Recent investigations have disclosed that LncRNAs transcripts play a pivotal role in the tumorigenesis.http://jabs.fums.ac.ir/article-1-1805-en.pdfprostate cancerlong non-coding rnalncrna |
spellingShingle | parisa Fouman Ajirloo arezo zaree saeid ghorbian The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer Journal of Advanced Biomedical Sciences prostate cancer long non-coding rna lncrna |
title | The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer |
title_full | The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer |
title_fullStr | The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer |
title_full_unstemmed | The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer |
title_short | The Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer |
title_sort | roles of long non coding rnas lncrna in prostate cancer |
topic | prostate cancer long non-coding rna lncrna |
url | http://jabs.fums.ac.ir/article-1-1805-en.pdf |
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