Pathogenesis of Type 1 Diabetes: Established Facts and New Insights

Pathogenesis of Type 1 Diabetes: Established Facts and New Insights

Type 1 diabetes (T1D) is an autoimmune disease characterized by the T-cell-mediated destruction of insulin-producing β-cells in pancreatic islets. It generally occurs in genetically susceptible individuals, and genetics plays a major role in the development of islet autoimmunity. Furthermore, these...

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Bibliographic Details
Main Authors: Ana Zajec, Katarina Trebušak Podkrajšek, Tine Tesovnik, Robert Šket, Barbara Čugalj Kern, Barbara Jenko Bizjan, Darja Šmigoc Schweiger, Tadej Battelino, Jernej Kovač
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Genes
Subjects:
type 1 diabetes
genetics
β-cell
epigenetics
viral infections
Online Access:https://www.mdpi.com/2073-4425/13/4/706

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