Identification and quantitation of clinically relevant microbes in patient samples: Comparison of three k-mer based classifiers for speed, accuracy, and sensitivity.
Infections are a serious health concern worldwide, particularly in vulnerable populations such as the immunocompromised, elderly, and young. Advances in metagenomic sequencing availability, speed, and decreased cost offer the opportunity to supplement or even replace culture-based identification of...
Main Authors: | George S Watts, James E Thornton, Ken Youens-Clark, Alise J Ponsero, Marvin J Slepian, Emmanuel Menashi, Charles Hu, Wuquan Deng, David G Armstrong, Spenser Reed, Lee D Cranmer, Bonnie L Hurwitz |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-11-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1006863 |
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