Multi-objective structural optimization and degradation model of magnesium alloy ureteral stent
Background: Mg alloys have attractive properties, including biocompatibility, biodegradability, and ideal mechanical properties. Moreover, Mg alloys are regarded as one of the promising candidates for manufacturing ureteral stents. This study proposed a multi-objective optimization method based on t...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-06-01
|
| Series: | Medicine in Novel Technology and Devices |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590093524000079 |
| _version_ | 1797249095554826240 |
|---|---|
| author | Lin Zhu Qiao Li Yuanming Gao Lizhen Wang Yubo Fan |
| author_facet | Lin Zhu Qiao Li Yuanming Gao Lizhen Wang Yubo Fan |
| author_sort | Lin Zhu |
| collection | DOAJ |
| description | Background: Mg alloys have attractive properties, including biocompatibility, biodegradability, and ideal mechanical properties. Moreover, Mg alloys are regarded as one of the promising candidates for manufacturing ureteral stents. This study proposed a multi-objective optimization method based on the Kriging surrogate model, NSGA-Ⅲ, and finite element analysis to improve the degradation performance of Mg alloy ureteral stents. Methods: The finite element model for the degradation of Mg alloy ureteral stents has been established to compare the degradation performance of the stents under different parameters. Latin hypercube sampling was adopted to generate train sample points in the design space. Meanwhile, the Kriging surrogate model was constructed between strut parameters and stent degradation behavior. The NSGA-Ⅲ was utilized to determine the optimal solution in the global design space. Results: The optimized stent achieved 5.52 × degradation uniformity (M), 10 × degradation time (DT), and 4 × work time (FT). The errors between the Kriging surrogate model and the finite element calculation results were less than 6%. Conclusion: The optimized stent achieved better degradation performance. The degradation behavior of stents was dependent on the design parameters. The multi-objective optimization method based on the Kriging surrogate model and finite element analysis was effective in stent design optimization problems. |
| first_indexed | 2024-04-24T20:25:02Z |
| format | Article |
| id | doaj.art-a4603c70e17944b1aa8ac5e8c1990841 |
| institution | Directory Open Access Journal |
| issn | 2590-0935 |
| language | English |
| last_indexed | 2024-04-24T20:25:02Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medicine in Novel Technology and Devices |
| spelling | doaj.art-a4603c70e17944b1aa8ac5e8c19908412024-03-22T05:40:33ZengElsevierMedicine in Novel Technology and Devices2590-09352024-06-0122100291Multi-objective structural optimization and degradation model of magnesium alloy ureteral stentLin Zhu0Qiao Li1Yuanming Gao2Lizhen Wang3Yubo Fan4Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, ChinaSchool of Engineering Medicine, Beihang University, Beijing, 100191, China; Corresponding author.School of Engineering Medicine, Beihang University, Beijing, 100191, ChinaKey Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China; School of Engineering Medicine, Beihang University, Beijing, 100191, ChinaKey Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China; School of Engineering Medicine, Beihang University, Beijing, 100191, ChinaBackground: Mg alloys have attractive properties, including biocompatibility, biodegradability, and ideal mechanical properties. Moreover, Mg alloys are regarded as one of the promising candidates for manufacturing ureteral stents. This study proposed a multi-objective optimization method based on the Kriging surrogate model, NSGA-Ⅲ, and finite element analysis to improve the degradation performance of Mg alloy ureteral stents. Methods: The finite element model for the degradation of Mg alloy ureteral stents has been established to compare the degradation performance of the stents under different parameters. Latin hypercube sampling was adopted to generate train sample points in the design space. Meanwhile, the Kriging surrogate model was constructed between strut parameters and stent degradation behavior. The NSGA-Ⅲ was utilized to determine the optimal solution in the global design space. Results: The optimized stent achieved 5.52 × degradation uniformity (M), 10 × degradation time (DT), and 4 × work time (FT). The errors between the Kriging surrogate model and the finite element calculation results were less than 6%. Conclusion: The optimized stent achieved better degradation performance. The degradation behavior of stents was dependent on the design parameters. The multi-objective optimization method based on the Kriging surrogate model and finite element analysis was effective in stent design optimization problems.http://www.sciencedirect.com/science/article/pii/S2590093524000079Mg alloys ureteral stentKriging surrogate modelNSGA-ⅢMulti-objective optimizationDegradation model |
| spellingShingle | Lin Zhu Qiao Li Yuanming Gao Lizhen Wang Yubo Fan Multi-objective structural optimization and degradation model of magnesium alloy ureteral stent Medicine in Novel Technology and Devices Mg alloys ureteral stent Kriging surrogate model NSGA-Ⅲ Multi-objective optimization Degradation model |
| title | Multi-objective structural optimization and degradation model of magnesium alloy ureteral stent |
| title_full | Multi-objective structural optimization and degradation model of magnesium alloy ureteral stent |
| title_fullStr | Multi-objective structural optimization and degradation model of magnesium alloy ureteral stent |
| title_full_unstemmed | Multi-objective structural optimization and degradation model of magnesium alloy ureteral stent |
| title_short | Multi-objective structural optimization and degradation model of magnesium alloy ureteral stent |
| title_sort | multi objective structural optimization and degradation model of magnesium alloy ureteral stent |
| topic | Mg alloys ureteral stent Kriging surrogate model NSGA-Ⅲ Multi-objective optimization Degradation model |
| url | http://www.sciencedirect.com/science/article/pii/S2590093524000079 |
| work_keys_str_mv | AT linzhu multiobjectivestructuraloptimizationanddegradationmodelofmagnesiumalloyureteralstent AT qiaoli multiobjectivestructuraloptimizationanddegradationmodelofmagnesiumalloyureteralstent AT yuanminggao multiobjectivestructuraloptimizationanddegradationmodelofmagnesiumalloyureteralstent AT lizhenwang multiobjectivestructuraloptimizationanddegradationmodelofmagnesiumalloyureteralstent AT yubofan multiobjectivestructuraloptimizationanddegradationmodelofmagnesiumalloyureteralstent |