Influence of Two Different Types of Cardioplegia on Hemodilution During and After Cardiopulmonary Bypass, Postoperative Chest-Drainage Bleeding and Consumption of Donor Blood Products
The aim of this study is to compare the effects of colloidal cardioplegia and blood cardioplegia in patients who underwent cardiac surgical procedures with cardiopulmonary bypass, and to evaluate their influence on hemodilution, bleeding and consumption of donor blood productsin a retrospective cli...
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| Format: | Article |
| Language: | English |
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2006-08-01
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| Series: | Biomolecules & Biomedicine |
| Subjects: | |
| Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3144 |
| _version_ | 1827317258521673728 |
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| author | Mirsad Kacila Katrin Schäfer Esad Subašić Nermir Granov Edin Omerbašić Faida Kučukalić Ermina Selimović-Mujčić |
| author_facet | Mirsad Kacila Katrin Schäfer Esad Subašić Nermir Granov Edin Omerbašić Faida Kučukalić Ermina Selimović-Mujčić |
| author_sort | Mirsad Kacila |
| collection | DOAJ |
| description |
The aim of this study is to compare the effects of colloidal cardioplegia and blood cardioplegia in patients who underwent cardiac surgical procedures with cardiopulmonary bypass, and to evaluate their influence on hemodilution, bleeding and consumption of donor blood productsin a retrospective clinical study. 100 male patients who underwent cardiac surgical procedure were divided into two groups: 50 patients were administered intermittent normotherm or mild hypotherm (34 degrees C) Calafiore blood cardioplegia with potassium chloride 14,9%; 50 patients were administered one initial doses of cold Kirsch - solution followed from intermittent cold colloidal cardioplegia using hydroxyethyl starch (HES 450/0,7). Hemoglobin values after the first dose of cardioplegia were significantly lower in the HES-group than in the Calafiore- group). After the first dose of cardioplegia platelets count was lower in the HES-group than in the Calafiore-group. Hemoglobin and hematocrit values 24h postoperative were lower in the HES-group than in the Calafiore-group. There was no difference in chest-drainagebleeding 12h and 24h postoperative between the groups. The consumption of donor erythrocyte concentrate and fresh frozen plasma was significantly higher in the HES-than in the Calafiore- group. The choice of either colloidal or blood cardioplegia does not influence the postoperative chest-drainage bleeding. The results suggest that high molecular colloidal cardioplegia with HES-solution is associated with higher hemodilution during and after cardiopulmonary bypass and significantly increases the consumption of donor blood products.
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| first_indexed | 2024-04-24T23:31:01Z |
| format | Article |
| id | doaj.art-a46138e914bf4dc9b41501a389f1326b |
| institution | Directory Open Access Journal |
| issn | 2831-0896 2831-090X |
| language | English |
| last_indexed | 2024-04-24T23:31:01Z |
| publishDate | 2006-08-01 |
| publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
| record_format | Article |
| series | Biomolecules & Biomedicine |
| spelling | doaj.art-a46138e914bf4dc9b41501a389f1326b2024-03-15T14:42:30ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2006-08-016310.17305/bjbms.2006.3144696Influence of Two Different Types of Cardioplegia on Hemodilution During and After Cardiopulmonary Bypass, Postoperative Chest-Drainage Bleeding and Consumption of Donor Blood ProductsMirsad Kacila0Katrin Schäfer1Esad Subašić2Nermir Granov3Edin Omerbašić4Faida Kučukalić5Ermina Selimović-Mujčić6Heart Center Sarajevo, University of Sarajevo Clinics CenterHeart Center Sarajevo, University of Sarajevo Clinics CenterHeart Center Sarajevo, University of Sarajevo Clinics CenterHeart Center Sarajevo, University of Sarajevo Clinics CenterHeart Center Sarajevo, University of Sarajevo Clinics CenterHeart Center Sarajevo, University of Sarajevo Clinics CenterHeart Center Sarajevo, University of Sarajevo Clinics Center The aim of this study is to compare the effects of colloidal cardioplegia and blood cardioplegia in patients who underwent cardiac surgical procedures with cardiopulmonary bypass, and to evaluate their influence on hemodilution, bleeding and consumption of donor blood productsin a retrospective clinical study. 100 male patients who underwent cardiac surgical procedure were divided into two groups: 50 patients were administered intermittent normotherm or mild hypotherm (34 degrees C) Calafiore blood cardioplegia with potassium chloride 14,9%; 50 patients were administered one initial doses of cold Kirsch - solution followed from intermittent cold colloidal cardioplegia using hydroxyethyl starch (HES 450/0,7). Hemoglobin values after the first dose of cardioplegia were significantly lower in the HES-group than in the Calafiore- group). After the first dose of cardioplegia platelets count was lower in the HES-group than in the Calafiore-group. Hemoglobin and hematocrit values 24h postoperative were lower in the HES-group than in the Calafiore-group. There was no difference in chest-drainagebleeding 12h and 24h postoperative between the groups. The consumption of donor erythrocyte concentrate and fresh frozen plasma was significantly higher in the HES-than in the Calafiore- group. The choice of either colloidal or blood cardioplegia does not influence the postoperative chest-drainage bleeding. The results suggest that high molecular colloidal cardioplegia with HES-solution is associated with higher hemodilution during and after cardiopulmonary bypass and significantly increases the consumption of donor blood products. https://www.bjbms.org/ojs/index.php/bjbms/article/view/3144cardiopulmonary bypassmyocardial protectioncardioplegiapostoperative bleedinghemodilution |
| spellingShingle | Mirsad Kacila Katrin Schäfer Esad Subašić Nermir Granov Edin Omerbašić Faida Kučukalić Ermina Selimović-Mujčić Influence of Two Different Types of Cardioplegia on Hemodilution During and After Cardiopulmonary Bypass, Postoperative Chest-Drainage Bleeding and Consumption of Donor Blood Products Biomolecules & Biomedicine cardiopulmonary bypass myocardial protection cardioplegia postoperative bleeding hemodilution |
| title | Influence of Two Different Types of Cardioplegia on Hemodilution During and After Cardiopulmonary Bypass, Postoperative Chest-Drainage Bleeding and Consumption of Donor Blood Products |
| title_full | Influence of Two Different Types of Cardioplegia on Hemodilution During and After Cardiopulmonary Bypass, Postoperative Chest-Drainage Bleeding and Consumption of Donor Blood Products |
| title_fullStr | Influence of Two Different Types of Cardioplegia on Hemodilution During and After Cardiopulmonary Bypass, Postoperative Chest-Drainage Bleeding and Consumption of Donor Blood Products |
| title_full_unstemmed | Influence of Two Different Types of Cardioplegia on Hemodilution During and After Cardiopulmonary Bypass, Postoperative Chest-Drainage Bleeding and Consumption of Donor Blood Products |
| title_short | Influence of Two Different Types of Cardioplegia on Hemodilution During and After Cardiopulmonary Bypass, Postoperative Chest-Drainage Bleeding and Consumption of Donor Blood Products |
| title_sort | influence of two different types of cardioplegia on hemodilution during and after cardiopulmonary bypass postoperative chest drainage bleeding and consumption of donor blood products |
| topic | cardiopulmonary bypass myocardial protection cardioplegia postoperative bleeding hemodilution |
| url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3144 |
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