Coordinated metabolic responses to cyclophilin D deletion in the developing heart

Summary: In the embryonic heart, the activation of the mitochondrial electron transport chain (ETC) coincides with the closure of the cyclophilin D (CypD) regulated mitochondrial permeability transition pore (mPTP). However, it remains to be established whether the absence of CypD has a regulatory e...

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Bibliographic Details
Main Authors: Gisela Beutner, Jonathan Ryan Burris, Michael P. Collins, Chaitanya A. Kulkarni, Sergiy M. Nadtochiy, Karen L. de Mesy Bentley, Ethan D. Cohen, Paul S. Brookes, George A. Porter, Jr.
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422400378X

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