Multi-trait genome-wide association analyses leveraging alcohol use disorder findings identify novel loci for smoking behaviors in the Million Veteran Program

Abstract Smoking behaviors and alcohol use disorder (AUD), both moderately heritable traits, commonly co-occur in the general population. Single-trait genome-wide association studies (GWAS) have identified multiple loci for smoking and AUD. However, GWASs that have aimed to identify loci contributin...

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Bibliographic Details
Main Authors: Youshu Cheng, Cecilia Dao, Hang Zhou, Boyang Li, Rachel L. Kember, Sylvanus Toikumo, Hongyu Zhao, Joel Gelernter, Henry R. Kranzler, Amy C. Justice, Ke Xu
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02409-2