DFS70/LEDGFp75: an enigmatic autoantigen at the interface between autoimmunity, AIDS, and cancer

DFS70/LEDGFp75: an enigmatic autoantigen at the interface between autoimmunity, AIDS, and cancer

Clinical and diagnostic laboratories often encounter patient sera containing antinuclear antibodies (ANAs) that produce a nuclear dense fine speckled immunofluorescence pattern on HEp-2 cells. These autoantibodies usually target the dense fine speckled protein of 70 kD (DFS70), commonly known as le...

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Bibliographic Details
Main Authors: Anamika eBasu, Tino Wilson Sanchez, Carlos A Casiano
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Immunology
Subjects:
Autoantibodies
Autoantigens
Autoimmunity
HIV
Cancer
DFS70
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00116/full

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