Cellular Model of Malignant Transformation of Primary Human Astrocytes Induced by Deadhesion/Readhesion Cycles

Cellular Model of Malignant Transformation of Primary Human Astrocytes Induced by Deadhesion/Readhesion Cycles

Astrocytoma is the most common and aggressive tumor of the central nervous system. Genetic and environmental factors, bacterial infection, and several other factors are known to be involved in gliomagenesis, although the complete underlying molecular mechanism is not fully understood. Tumorigenesis...

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Bibliographic Details
Main Authors: Roseli da S. Soares, Talita de S. Laurentino, Camila T. da Silva, Jéssica D. Gonçalves, Antonio M. Lerario, Suely K. N. Marie, Sueli M. Oba-Shinjo, Miriam G. Jasiulionis
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
malignant transformation
astrocytes
glioblastoma
<i>anoikis</i> resistance
tumor progression
Online Access:https://www.mdpi.com/1422-0067/23/9/4471

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