Influence of the DASH Diet on Gestational Weight Gain and Perinatal Outcomes in Women with Pre-Existing Diabetes Mellitus: A Randomized, Single-Blind, Controlled Clinical Trial
Background: This study aimed to investigate the influence of the dietary approaches to stop hypertension (DASH) diet on gestational weight gain and perinatal outcomes in pregnant women with pre-existing diabetes mellitus (PDM). Methods: A randomized, single-blind, controlled clinical trial was condu...
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| Format: | Article |
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MDPI AG
2023-11-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/11/2191 |
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| author | Gabriella P. Belfort Dayana R. Farias Patricia de C. Padilha Letícia B. G. da Silva Karina dos Santos Mayara S. dos Santos Lenita Zajdenverg Elisa Keating Claudia Saunders |
| author_facet | Gabriella P. Belfort Dayana R. Farias Patricia de C. Padilha Letícia B. G. da Silva Karina dos Santos Mayara S. dos Santos Lenita Zajdenverg Elisa Keating Claudia Saunders |
| author_sort | Gabriella P. Belfort |
| collection | DOAJ |
| description | Background: This study aimed to investigate the influence of the dietary approaches to stop hypertension (DASH) diet on gestational weight gain and perinatal outcomes in pregnant women with pre-existing diabetes mellitus (PDM). Methods: A randomized, single-blind, controlled clinical trial was conducted with 68 pregnant women with PDM throughout prenatal care until delivery (18 weeks) at a public maternity hospital in Rio de Janeiro, Brazil (2016–2020). The standard diet adopted by the control group (standard diet group—SDG) contained 45–55% carbohydrates, 15–20% protein, and 25–30% lipids of the total energy intake. An adapted DASH diet, with a similar macronutrient composition, but with higher calcium, potassium, magnesium, fiber, and reduced saturated fat, was prescribed for the intervention group (DASH diet group—DDG). Student’s <i>t</i>- or Mann–Whitney <i>U</i> tests were used to compare outcomes between groups. To assess the trajectory of gestational weight gain throughout the intervention between the study groups, linear mixed-effects regression models were used. Results: The DDG had lower gestational weight gain at the fifth (<i>p</i> = 0.03) and seventh appointment (<i>p</i> = 0.04), with no difference in average total gestational weight gain (SDG: 10 kg [SD = 4]; DDG: 9 kg [SD = 5], <i>p</i> = 0.23). There was a trend for a lower length of stay of the newborns (<i>p</i> = 0.08) in the DDG without differences for other perinatal outcomes. Conclusions: The DASH diet promoted less variation in gestational weight gain without promoting a difference in total gestational weight gain, and there was no difference between the study groups for perinatal outcomes. |
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| id | doaj.art-a47d8f2475e84c31bd35c0a927d704dc |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-09T16:40:17Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-a47d8f2475e84c31bd35c0a927d704dc2023-11-24T14:52:32ZengMDPI AGLife2075-17292023-11-011311219110.3390/life13112191Influence of the DASH Diet on Gestational Weight Gain and Perinatal Outcomes in Women with Pre-Existing Diabetes Mellitus: A Randomized, Single-Blind, Controlled Clinical TrialGabriella P. Belfort0Dayana R. Farias1Patricia de C. Padilha2Letícia B. G. da Silva3Karina dos Santos4Mayara S. dos Santos5Lenita Zajdenverg6Elisa Keating7Claudia Saunders8Postgraduate Program in Nutrition, Josué de Castro Institute of Nutrition, Federal University of Rio de Janeiro, Carlos Chagas Filho Ave, 373, University City, Rio de Janeiro 21941-590, RJ, BrazilPostgraduate Program in Nutrition, Josué de Castro Institute of Nutrition, Federal University of Rio de Janeiro, Carlos Chagas Filho Ave, 373, University City, Rio de Janeiro 21941-590, RJ, BrazilPostgraduate Program in Nutrition, Josué de Castro Institute of Nutrition, Federal University of Rio de Janeiro, Carlos Chagas Filho Ave, 373, University City, Rio de Janeiro 21941-590, RJ, BrazilPostgraduate Program in Nutrition, Josué de Castro Institute of Nutrition, Federal University of Rio de Janeiro, Carlos Chagas Filho Ave, 373, University City, Rio de Janeiro 21941-590, RJ, BrazilPostgraduate Program in Nutrition, Josué de Castro Institute of Nutrition, Federal University of Rio de Janeiro, Carlos Chagas Filho Ave, 373, University City, Rio de Janeiro 21941-590, RJ, BrazilMaternity School of the Federal University of Rio de Janeiro, Laranjeiras Street, 180, Rio de Janeiro 22240-003, RJ, BrazilMaternity School of the Federal University of Rio de Janeiro, Laranjeiras Street, 180, Rio de Janeiro 22240-003, RJ, BrazilUnit of Biochemistry, Department of Biomedicine, Faculty of Medicine, University of Porto, Prof. Hernâni Monteiro Ave, 4200-319 Porto, PortugalPostgraduate Program in Nutrition, Josué de Castro Institute of Nutrition, Federal University of Rio de Janeiro, Carlos Chagas Filho Ave, 373, University City, Rio de Janeiro 21941-590, RJ, BrazilBackground: This study aimed to investigate the influence of the dietary approaches to stop hypertension (DASH) diet on gestational weight gain and perinatal outcomes in pregnant women with pre-existing diabetes mellitus (PDM). Methods: A randomized, single-blind, controlled clinical trial was conducted with 68 pregnant women with PDM throughout prenatal care until delivery (18 weeks) at a public maternity hospital in Rio de Janeiro, Brazil (2016–2020). The standard diet adopted by the control group (standard diet group—SDG) contained 45–55% carbohydrates, 15–20% protein, and 25–30% lipids of the total energy intake. An adapted DASH diet, with a similar macronutrient composition, but with higher calcium, potassium, magnesium, fiber, and reduced saturated fat, was prescribed for the intervention group (DASH diet group—DDG). Student’s <i>t</i>- or Mann–Whitney <i>U</i> tests were used to compare outcomes between groups. To assess the trajectory of gestational weight gain throughout the intervention between the study groups, linear mixed-effects regression models were used. Results: The DDG had lower gestational weight gain at the fifth (<i>p</i> = 0.03) and seventh appointment (<i>p</i> = 0.04), with no difference in average total gestational weight gain (SDG: 10 kg [SD = 4]; DDG: 9 kg [SD = 5], <i>p</i> = 0.23). There was a trend for a lower length of stay of the newborns (<i>p</i> = 0.08) in the DDG without differences for other perinatal outcomes. Conclusions: The DASH diet promoted less variation in gestational weight gain without promoting a difference in total gestational weight gain, and there was no difference between the study groups for perinatal outcomes.https://www.mdpi.com/2075-1729/13/11/2191diabetes mellitusdietary approaches to stop hypertensionfetal macrosomiagestational weight gain |
| spellingShingle | Gabriella P. Belfort Dayana R. Farias Patricia de C. Padilha Letícia B. G. da Silva Karina dos Santos Mayara S. dos Santos Lenita Zajdenverg Elisa Keating Claudia Saunders Influence of the DASH Diet on Gestational Weight Gain and Perinatal Outcomes in Women with Pre-Existing Diabetes Mellitus: A Randomized, Single-Blind, Controlled Clinical Trial Life diabetes mellitus dietary approaches to stop hypertension fetal macrosomia gestational weight gain |
| title | Influence of the DASH Diet on Gestational Weight Gain and Perinatal Outcomes in Women with Pre-Existing Diabetes Mellitus: A Randomized, Single-Blind, Controlled Clinical Trial |
| title_full | Influence of the DASH Diet on Gestational Weight Gain and Perinatal Outcomes in Women with Pre-Existing Diabetes Mellitus: A Randomized, Single-Blind, Controlled Clinical Trial |
| title_fullStr | Influence of the DASH Diet on Gestational Weight Gain and Perinatal Outcomes in Women with Pre-Existing Diabetes Mellitus: A Randomized, Single-Blind, Controlled Clinical Trial |
| title_full_unstemmed | Influence of the DASH Diet on Gestational Weight Gain and Perinatal Outcomes in Women with Pre-Existing Diabetes Mellitus: A Randomized, Single-Blind, Controlled Clinical Trial |
| title_short | Influence of the DASH Diet on Gestational Weight Gain and Perinatal Outcomes in Women with Pre-Existing Diabetes Mellitus: A Randomized, Single-Blind, Controlled Clinical Trial |
| title_sort | influence of the dash diet on gestational weight gain and perinatal outcomes in women with pre existing diabetes mellitus a randomized single blind controlled clinical trial |
| topic | diabetes mellitus dietary approaches to stop hypertension fetal macrosomia gestational weight gain |
| url | https://www.mdpi.com/2075-1729/13/11/2191 |
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